摘要
目的:分析清热润目汤熏蒸辅助按摩治疗睑板腺功能障碍性干眼症的临床疗效及安全性研究。方法:选取2021年9月~2022年9月我院收治的睑板腺功能障碍性干眼症患者80例,根据治疗方式的不同分为对照组40例(在一般治疗基础上予蒸馏水熏蒸联合睑板腺按摩)和观察组40例(在一般治疗基础上予清热润目汤熏蒸联合睑板腺按摩治疗)。对比两组临床疗效、疗效性指标、基础泪液分泌实验(Schirmer I test,SIT)评分、角膜上皮荧光染色(Fluorescent,FL)评分、泪膜破裂时间(Break-up time,BUT)评分、以及不良反应发生率。结果:观察组(93.12%)总有效率高于对照组(75.00%)(P<0.05);治疗后两组主观症状评分、睑板腺功能评分、FL评分均降低,SIT评分、BUT评分均上升,泪膜破裂时间延长,且观察组治疗后主观症状评分、睑板腺功能评分、FL评分均低于对照组,SIT评分、BUT评分高于对照组,泪膜破裂时间长于对照组(P<0.05);观察组(12.20%)不良反应发生率高于对照组(5.00%),但差异无统计学意义(P>0.05)。结论:清热润目汤熏蒸联合睑板腺按摩治疗睑板腺功能障碍性干眼症更加具有标本同治的优势,可改善干眼症状、延长泪膜破裂时间,从而使疗效得以提升,可为临床上治疗睑板腺功能障碍提供新思路。
Objective To analyze the clinical relationship and safety of Qingre Runmu Decoction fumigation assisted massage in the treatment of meibomian gland dysfunction dry eye syndrome.Methods 80patients with meibomian gland dysfunction dry eye who were admitted to our hospital from September 2021to September 2022were selected,and according to different treatment methods,they were divided into 40cases in the control group(distilled water fumigation combined with meibomian gland massage on the basis of general treatment)and 40cases in the observation group(fumigation with Qingre Runmu Decoction combined with meibomian gland massage on the basis of general treatment).The clinical curative effect,curative effect indexes,basic tear Schirmer I test(SIT)score,corneal epithelial Fluorescent(FL)score,tear film break-up time(BUT)score,and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group(93.12%)was higher than that of the control group(75.00%)(P<0.05);after treatment,the subjective symptom scores,meibomian gland function scores,and FL scores of the two groups decreased,while SIT scores and BUT scores increased,the tear film breakup time was prolonged,and the subjective symptom score,meibomian gland function score,and FL score of the observation group were lower than those of the control group after treatment,the SIT score and BUT score of the observation group were higher than those of the control group,and the tear film breakup time of the observation group was longer than that of the control group(P<0.05);the incidence of adverse reactions in the observation group(12.20%)was higher than that in the control group(5.00%),but the difference was not statistically significant(P>0.05).Conclusion Qingren Runmu Decoction fumigation combined with meibomian gland massage in the treatment of meibomian gland dysfunction dry eye has more advantages of specimen treatment,can improve the symptoms of dry eye,prolong the time of tear film rupture,so as to improve th
作者
王春梅
乔玉培
宗瑞琪
贾俊
赵桂霞
孙彩英
刘化峰
WANG Chunmei;QIAO Yupei;Zong Ruiqi(Affiliated Eye Hospital of North China University of Technology/Hebei Tangshan Eye Hospital/Hebei Tangshan Eye Research Institute,Tangshan Hebei 063000,China)
出处
《四川中医》
2024年第7期172-175,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
河北省中医药管理局中医药类指导性科研计划项目(编号:2022563)。
关键词
清热润目汤熏蒸
按摩
睑板腺功能障碍性干眼症
安全性
Qingre Runmu decoction fumigation
massage
meibomian gland dysfunction dry eye
safety
