摘要
目的:探讨原发性骨质疏松症患者的中医证候以及证素分布规律。方法:检索中国知网以及万方数据库中有关原发性骨质疏松症中医证型的相关文献,检索时间为数据库建立至2023年5月。应用Excel表提取原发性骨质疏松症患者的中医证型信息,将文献中证型的名称规范化处理,对中医证型进行证素提取,建立数据库,采用SPSS 27.0.1软件进行频数分析。结果:共纳入79篇符合标准的文献,病例18251例,经规范化处理后共纳入41种中医证型,16种证素,其中病位证素4种,病性证素12种。在总的证型分布中频率>3%的证型有8种,其中肝肾阴虚证居首位,4017例(22.05%),其余是脾肾阳虚证3236例(17.77%)、气滞血瘀证1733例(9.51%)、肾阳虚证1631例(8.95%)、肾虚血瘀证1433例(7.87%)、脾肾两虚证1087例(5.97%)、气虚血瘀证594例(3.26%)、脾肾气虚证549例(3.01%)。在总的证素分布中,病位证素分别是肾13700例(56.00%)、脾5720例(23.26%)、肝4454例(18.11%)、胃646例(2.63%);病性证素分别是阳虚5301例(27.92%)、阴虚4851例(25.55%)、血瘀4139例(21.80%)、气滞1759例(9.26%)、气虚1700例(8.95%)、精亏606例(3.19%),其余6个病性证素出现频率较小(频率均<3.00%)。结论:原发性骨质疏松症的病位主要分布在肾、脾、肝、胃,其证素分布虚实夹杂,虚证以阳虚、阴虚、气虚为主,实证则以血瘀、气滞为主,中医证型以肝肾阴虚证、脾肾阳虚证、气滞血瘀证、肾阳虚证最为常见。原发性骨质疏松症的病机、证候复杂多样,而中医证型有时难以完全体现患者的具体情况,证素的合理搭配能有效地应对复杂的病机及证候。
Objective:To explore the TCM syndromes and the distribution patterns of syndrome elements in patients with primary osteoporosis.Methods:Relevant literature on the TCM syndrome types of primary osteoporosis was retrieved from the databases CNKI and Wanfang(the retrieval time was from the establishment of the databases to May 2023).Excel tables were used to extract the TCM syndrome type information of different patients with primary osteoporosis.The names of the syndrome types in the literature were standardized,syndrome elements were extracted from the TCM syndrome types,a database was established,and frequency analysis was performed using software SPSS 27.0.1 respectively.Results:A total of 79 eligible literatures were included,with 18251 cases.After standardization,a total of 41 TCM syndrome types and 16 syndrome elements were included,including 4 disease location syndrome elements and 12 disease nature syndrome elements.Among the total syndrome type distribution,there were 8 syndrome types with a frequency more than 3%.Among them,the liver-kidney yin deficiency syndrome ranked first,with 4017 cases(22.05%),followed by the spleen-kidney yang deficiency syndrome with 3236 cases(17.77%),the qi stagnation and blood stasis syndrome with 1733 cases(9.51%),the kidney yang deficiency syndrome with 1631 cases(8.95%),the kidney deficiency and blood stasis syndrome with 1433 cases(7.87%),the spleen-kidney deficiency syndrome with 1087 cases(5.97%),the qi deficiency and blood stasis syndrome with 594 cases(3.26%),and the spleen-kidney qi deficiency syndrome with 549 cases(3.01%).Among the total syndrome element distribution,the disease location syndrome elements were the kidney in 13700 cases(56.00%),the spleen in 5720 cases(23.26%),the liver in 4454 cases(18.11%),and the stomach in 646 cases(2.63%);the disease nature syndrome elements were yang deficiency in 5301 cases(27.92%),yin deficiency in 4851 cases(25.55%),blood stasis in 4139 cases(21.80%),qi stagnation in 1759 cases(9.26%),qi deficiency in 1700 cases(8.95%),essen
作者
李坤健
章晓云
柴源
曾浩
LI Kun-jian;ZHANG Xiao-yun;CHAI Yuan;ZENG Hao
出处
《风湿病与关节炎》
2024年第8期11-16,共6页
Rheumatism and Arthritis
关键词
原发性骨质疏松症
中医证型
证素
病位
病性
文献研究
primary osteoporosis
TCM syndrome types
syndrome element
disease location
disease nature
literature study
