摘要
目的:分析彩色多普勒定量分析腘动脉参数在2型糖尿病(T2DM)患者下肢血管病变中的应用价值。方法:采用回顾性分析法,将天津市河西医院2019年8月—2022年10月进行健康体检的25例志愿者纳入对照组,将51例T2MD患者纳入观察组。按腘动脉中膜厚度(IMT)情况将观察组分为A组(IMT正常)20例、B组(IMT增厚)6例、C组(斑块形成)25例。对比观察组与对照组患者腘动脉最大管径(R)、峰值血流速(peak systolic velocity,PSV)、壁剪应力(wall shear stress,WSS),对比A组、B组、C组患者病程、年龄、体重指数、血压、血糖等可能影响动脉斑块形成的因素,对比三组患者R、PSV、WSS。分析WSS预测T2DM患者效能以及WSS相关因素。结果:观察组患者PSV、WSS低于对照组,差异有统计学意义(P<0.05)。与A组比较,B组患者年龄更高,病程更长,甘油三酯、WSS更低,差异有统计学意义(P<0.05)。与A组比较,C组患者年龄更高,病程更长,PSV、WSS更低,差异有统计学意义(P<0.05)。与B组比较,C组患者年龄更高,PSV、WSS更低,差异有统计学意义(P<0.05)。WSS取1.82 dyne/cm^(2),预测T2DM患者下肢血管病变的特异度、灵敏度分别为84%、66%。WSS与病程、年龄、腘动脉IMT呈负相关(r=-0.370、-0.570、-0.592,P<0.05),与PSV呈正相关(r=0.601,P<0.05)。结论:彩色多普勒超声定量分析下腘动脉WSS能有效预测T2DM患者下肢血管病变,建议综合患者病程、年龄及腘动脉IMT提高诊断准确性。
Objective:To analyze the value of color Doppler quantification of popliteal artery parameters in lower extremity vasculopathy in patients with type 2 diabetes mellitus(T2DM).Methods:Using retrospective analysis,volunteers who underwent health checkups in the hospital from August 2019 to October 2022 were included in the control group(25 cases),and patients with T2MD were included in the observation group(51 cases).The observation group was divided into 20 cases in group A(normal IMT),6 cases in group B(IMT thickening),and 25 cases in group C(plaque formation)according to the popliteal artery intima-media thickness(IMT).The maximum diameter of popliteal artery(R),peak systolic velocity(PSV),wall shear stress(WSS)were compared between the observation group and the control group.The disease duration,age,body mass index,blood pressure,and blood glucose,etc.,which may affect the formation of arterial plaque,were compared among patients in Groups A,B and C.R,PSV and WSS were compared among the three groups.WSS was analyzed to predict the efficacy of type 2 diabetes mellitus and the factors associated with WSS.Results:PSV and WSS of patients in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Compared with Group A,patients in Group B were older,had a longer disease duration,and had lower triglycerides and WSS,and the difference was statistically significant(P<0.05).Compared with group A,patients in group C were higher in age,had a longer disease duration,and lower PSV and WSS,and the difference was statistically significant(P<0.05).Compared with group B,patients in group C were higher in age and had lower PSV and WSS,and the difference was statistically significant(P<0.05).WSS was taken as 1.82 dyne/cm^(2),with a specificity and sensitivity of 84%and 66%,respectively,predicting LEAD in patients with T2DM was negatively correlated with disease duration,age,and popliteal artery IMT(r=-0.370,-0.570,-0.592;P<0.05),and positively correlated with PSV(r=0
作者
马林
Ma Lin(Ultrasound Department,Hexi Hospital,Tianjin,300202,China)
出处
《黑龙江医学》
2024年第16期1976-1979,共4页
Heilongjiang Medical Journal
关键词
下肢动脉血管病变
2型糖尿病
腘动脉
彩色多普勒超声
壁剪切应力
Lower extremity arterial vascular disease
Type 2 diabetes mellitus
Popliteal artery
Color Doppler ultrasound
Wall shear stress
