摘要
目的:分析肌酸激酶同工酶(CK-MB)、肌红蛋白(MYO)、肌钙蛋白I(cTnI)、N末端B型脑钠肽前体(NT-proBNP)联合检测在急性心肌梗死(AMI)早期诊断中的价值。方法:选取2021年4月—2023年4月河南省南召县人民医院收治的97例AMI患者选入观察组,另将同期于医院行健康体检的85例健康者选入对照组,抽取两组受检者入院时的静脉血,检测对比两组受检者CK-MB、MYO、cTnI、NT-proBNP的差异;另描绘受检者工作曲线(ROC),分析CK-MB、MYO、cTnI、NT-proBNP单独或联合检测诊断AMI的效能。结果:观察组患者CK-MB、MYO、cTnI、NT-proBNP高于对照组,差异有统计学意义(t=55.086、49.389、50.232、46.301,P<0.05);ROC结果显示,CK-MB、MYO、cTnI、NT-proBNP联合检测诊断AMI的曲线下面积(AUC)为0.946,高于四者单独诊断的0.843、0.822、0.814、0.837。结论:CK-MB、MYO、cTnI、NT-proBNP在AMI患者机体内呈异常的高表达,四者联合能够有效的诊断出AMI,为临床提供有效的参考依据。
Objective:To analyze the value of Creatine kinase Isozyme(CK-MB),Myoglobin(MYO),Troponin I(cTnI)and N-terminal B-type pro brain natriuretic peptide(NT-proBNP)in the joint detection of acute myocardial infarction(AMI).Methods:97 AMI patients admitted to the hospital from April 2021 to April 2023 were assigned to the observation group,and 85 healthy individuals who underwent physical examinations in the hospital during the same period were assigned to the control group.Venous blood samples were collected from the two groups at admission,and the differences in CK-MB,MYO,cTnI and NT-proBNP between the two groups were measured and compared.Additionally,the receiver operating curve(ROC)was drawn and the efficacy of CK-MB,MYO,cTnI and NT-proBNP alone or in combination for the diagnosis of AMI were analyzed.Results:CK-MB,MYO,cTnI and NT-proBNP levels in the observation group were significantly higher than those in the control group,with statistically significant difference(t=55.086,49.389,50.232,46.301;P<0.05).The ROC results showed that CK-MB,MYO,cTnI and NT-proBNP in the diagnosis of AMI was higher than 0.843,0.822,0.814 and 0.837 diagnosed separately by the four.Conclusion:CK-MB,MYO,cTnI,and NT-proBNP exhibit abnormally high expression in the body of AMI patients.The combination of the four can effectively diagnose AMI and provide effective reference for clinical practice.
作者
廖青玲
Liao Qingling(Medical Laboratory Department,Nanzhao County People’s Hospital,Nanzhao,Henan,474650,China)
出处
《黑龙江医学》
2024年第15期1844-1846,共3页
Heilongjiang Medical Journal
关键词
急性心肌梗死
肌酸激酶同工酶
肌红蛋白
肌钙蛋白I
脑钠肽
诊断效能
Acute myocardial infarction
Creatine kinase Isozyme
Myoglobin
Troponin I
Brain natriuretic peptide
Diagnostic effectiveness
