摘要
硼中子俘获治疗(Boron Neutron Capture Therapy,BNCT)是一种新型的治疗肿瘤的方法,目前在治疗复发性头颈部肿瘤、胶质瘤和恶性黑色素瘤方面有突出的优势。本文从BNCT技术原理、发展历史、含硼药物、治疗副作用、中子产生方式及中子源、国内外的批准上市情况等多方面对BNCT技术的发展现状进行阐述,并对该项治疗技术进行展望。本文通过对BNCT技术发展现状进行综述,增进相关行业医务人员、研发人员、监管人员等对BNCT的了解,为中国BNCT技术发展、相关技术指南或规范的建立提供参考,推动中国的BNCT早日服务于广大的肿瘤患者。
Boron neutron capture therapy(BNCT)is a new method to treat tumors,and it has outstanding advantages in the treatment of recurrent head and neck tumor,glioma and malignant melanoma at present.This paper described the development status of BNCT technology from the aspects of its principle,development history,boron-containing drugs,side effects of treatment,neutron generation mode and neutron sources,approval for marketing domestically and internationally,and provided future prospects for this treatment technology,and provided a review of the current development status of BNCT technology,in order to enhance the understanding of medical personnel,research and development personnel,regulatory personnel,and other relevant industries on BNCT.It aims to provide reference for the development of BNCT technology,the establishment of relevant technical guidelines,or specifications in China,so as to promote the early service of Chinese BNCT for the vast number of tumor patients.
作者
谷晓芳
贺丽萍
杨鹏飞
王颖
GU Xiaofang;HE Liping;YANG Pengfei;WANG Ying(Center for Medical Device Evaluation.NMPA,Beijing 100081,China)
出处
《中国医疗设备》
2024年第8期152-158,共7页
China Medical Devices
基金
国家重点研发计划(2022YFC2409505)。
关键词
硼中子俘获治疗
含硼药物
中子源
批准上市
boron neutron capture therapy
boron-containing drugs
neutron source
approval and marketing
