摘要
2019年底新型冠状病毒感染(COVID-19)在世界范围内迅速传播。国内外许多相关研究报道多数COVID-19已康复的患者存在全身多个系统的长期并发症和后遗症,即长新冠综合征(以下简称长新冠)。核医学显像在评估多系统累及和长期后遗症的发生发展机制及预后方面有很大潜力,可指导长新冠治疗策略的制定和治疗反应的评估。笔者就核医学显像在长新冠中的研究进展进行综述,通过总结现有关于长新冠的基础研究和临床转化研究结果,推动长新冠的病理生理学机制研究,促进长新冠的诊断和管理,以提高长新冠患者的生存质量。
Coronavirus disease-2019(COVID-19)has spread rapidly around the world since its outbreak in late 2019.Many relevant studies at home and abroad have reported that most of the patients who have recovered from COVID-19 have long-term complications and sequelae of multiple systems throughout the body,that is,long COVID-19 syndrome(hereinafter referred to as long COVID-19).Nuclear medicine imaging has great potential in evaluating the occurrence,development mechanism and prognosis of multi-system involvement and long-term sequelae,which can guide the treatment strategy of long COVID-19 and evaluate the treatment response.The authors review the research progress of nuclear medicine imaging in long COVID-19.By summarizing the existing basic research and clinical transformation,the authors can promote the research on the pathophysiological mechanism of long COVID-19,so as to promote the diagnosis and management of long COVID-19,and improve the quality of life of the patients with long COVID-19.
作者
杨炜华
胡奕奕
马柠
武志芳
Yang Weihua;Hu Yiyi;Ma Ning;Wu Zhifang(Department of Nuclear Medicine,the First Hospital of Shanxi Medical University,Collaborative Innovation Center for Molecular Imaging,Taiyuan 030001,China)
出处
《国际放射医学核医学杂志》
2024年第6期381-385,共5页
International Journal of Radiation Medicine and Nuclear Medicine
基金
国家自然科学基金(U22A6008、81971655、82027804)
中央引导地方科技发展资金项目(YDZJSX2021B013)
山西省卫生健康委员会新冠科研项目(2023XG021)
2023年度山西省研究生科研创新项目(2023KY421)。
