摘要
农药残留检测是保障食品质量安全的重要工作,气相色谱串联质谱法或液相色谱串联质谱法因其准确性高被广泛用于农药残留检测,但基质效应会影响检测结果的准确性。为确保农药残留分析结果的准确和可靠,需要评估和消除或补偿基质效应。影响基质效应的主要因素有农药性质和结构、农药的浓度、基质的种类、检测仪器类型和色谱及质谱条件。补偿基质效应的措施有直接稀释法、内标法、分析保护剂法、基质匹配标准溶液校正法、基质净化法、标准添加法和代表基质补偿法等。文章综述了基质效应的定义与形成机制、基质效应的评价方法、基质效应的影响因素和基质效应补偿方法,以期为农药残留检测中因基质效应引起的不确定性提供参考。
Pesticide residue detection is an important task in ensuring food safety.Gas chromatography-tandem mass spectrometry (GC-MS/MS) and liquid chromotography-tandem mass spectrometry (LC-MS/MS) are widely used for pesticide residue detection due to their high accuracy.However,matrix effects can affect the accuracy of the detection results.In order to ensure the accuracy and reliability of pesticide residue analysis results,it is necessary to evaluate and mitigate or compensate for matrix effects.The main factors affecting matrix effects include pesticide properties and structures,pesticide concentrations,matrix types,types of detection instruments,and chromatographic and mass spectrometric conditions.Measures to compensate for matrix effects include direct dilution method,internal standard method,analysis protector method,matrix-matching standard solution correction method,matrix purification method,standard addition method,and representative matrix compensation method.The paper reviews the definition and formation mechanisms of matrix effects,evaluation methods,factors influencing matrix effects,and compensation strategies,aiming to provide insights into addressing the uncertainties caused by matrix effects in pesticide residue detection.
作者
闫君
陈婷
张婕
张新中
赵波
张文
YAN Jun;CHEN Ting;ZHANG Jie;ZHANG Xinzhong;ZHAO Bo;ZHANG Wen(Key Laboratory of Pesticide and Veterinary Drug Monitoring for State Market Regulation,Gansu Engineering Research Center for Monitoring Exogenous Harmful Residues in Traditional Chinese Medicines,Lanzhou Institute for Food and Drug Control,Lanzhou 730050,China)
出处
《食品科技》
CAS
北大核心
2024年第6期335-341,共7页
Food Science and Technology
基金
兰州市青年科技人才创新项目(2023-QN-100)
兰州市科技计划项目(2023-3-29)。
关键词
农药残留
基质效应
气相色谱串联质谱法
液相色谱串联质谱法
pesticide residue
matrix effect
gas chromatography-tandem mass spectrometry
liquid chromotography-tandem mass spectrometry
