摘要
目的探讨新乡医学院第一附属医院收治的胃癌的临床病理特征。方法回顾性分析2019年5月至2023年4月该院收治的661例连续胃癌手术病例临床病理资料。统计分析年龄、性别、癌肿部位、pT分期、淋巴结转移及脉管癌栓、神经侵犯情况。结果661例胃癌病例中男性499例,女性162例。661例胃癌患者年龄多处于46岁~75岁之间,56岁~70岁为发病高峰,平均年龄为(63.03±9.07)岁,其中男性平均年龄为(63.23±8.95)岁,女性平均年龄为(62.42±9.44)岁。不同性别组年龄相比差异无统计学意义(P>0.05)。癌肿部位以食管胃结合部腺癌为主(72.61%),不同性别组胃癌癌肿分布部位差异无统计学意义(P>0.05)。组织学类型以腺癌为主(98.18%);分化程度以低-中分化胃癌为主(88.65%)。胃癌T分期pT3组和pT4a组分别占39.49%和31.47%,随着pT分期的升高,淋巴结转移、神经侵犯、脉管癌栓阳性率逐渐增高,其中,pT3组与pT2组相比,淋巴结转移、神经侵犯、脉管癌栓阳性率差异均有统计学意义(P<0.05)。胃癌癌肿部位不同,淋巴结转移、神经侵犯、脉管癌栓阳性率无显著差别(P>0.05)。结论该院收治的胃癌的临床病理特征如下:多见于中老年男性;以食管胃结合部腺癌为主;分化程度以低-中分化腺癌为主,且与胃癌的原发部位无关;T分期多为T3和T4a期;淋巴结转移、神经侵犯、脉管癌栓的发生与T分期呈正相关,但不同部位胃癌的淋巴结转移、神经侵犯和脉管癌栓发生无明显差异。
Objective To summarize the clinicopathologic features of gastric cancer.Methods The clinical and pathological data of 661 patients with gastric cancer were analyzed retrospectively.Age,sex,tumor site,PT Staging,lymph node metastasis,vascular tumor thrombus and nerve invasion were analyzed statistically.Results There were 499 males and 162 females among the 661 cases of gastric cancer patients.The mean age of diagnosis of 661 gastric cancer patients was(63.03±9.07)years,the mean age of male patients was(63.23±8.95)years,the mean age of female patients was(62.42±9.44)years.There was no significant difference in the age between different sex groups(P>0.05).Most of them were between 46 and 75 years old,and the peak of age was from 56 to 70 years old.The majority(72.61%)of the gastric cancer tumors were adenocarcinoma of the esophagogastric junction.There was no significant difference in the distribution of gastric cancer in different sex groups(P>0.05).The histological type of gastric cancer was mainly adenocarcinoma(98.18%).The degree of differentiation was mainly poorly-moderately differentiated type(88.65%).The T stage of gastric cancer was 39.49%in pT3 group and 31.47%in pT4a group.With the increase of pT Stage,the incidence of lymph node metastasis and nerve invasion and vascular tumor thrombus increased gradually.Compared with pT2 group,the incidence of lymph node metastasis and perineural invasion and lymphovascular invasion in pT3 group were significantly different(P<0.05).There was no significant difference in the positive rates of lymph node metastasis,perineural invasion and lymphovascular invasion in different locations of gastric cancer(P>0.05).Conclusion Some clinicopathological features of gastric carcinoma are as follows:Most of them were found in middle-aged and old men;most of them are adenocarcinoma of the esophagogastric junction;The degree of differentiation is mainly poorly-moderately differentiated adenocarcinoma,and is not related to the primary site of gastric cancer.Most of T stage are T3
作者
李岩
吴新军
侯栋
孙培胜
郜庆祖
陈炳合
闫争强
LI Yan;WU Xinjun;HOU Dong(The First Affiliated Hospital of Xinxiang Medical University,Xinxiang,453100)
出处
《实用癌症杂志》
2024年第8期1342-1346,共5页
The Practical Journal of Cancer
关键词
胃肿瘤
临床病理特征
Stomach neoplasms
Clinicopathological feature
