摘要
目的:探究子宫动脉搏动指数(ultrasound uterine artery pulsation index,UtA-PI)、子宫动脉阻力指数(uterine artery resistance index,UtA-RI)联合血清肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、人绒毛膜促性腺激素(human chorionic gonadotrophin,hCG)在凶险性前置胎盘合并胎盘植入中的诊断价值。方法:选取2020年1月—2022年2月于阳春市人民医院进行检查并确诊为凶险性前置胎盘合并胎盘植入的52例孕妇为观察组,另选取52例同期来本院进行健康产检的正常孕妇作为对照组。所有孕妇均进行子宫动脉超声检查,记录并比较两组孕妇的UtA-PI、UtA-RI;采用酶联免疫法对两组孕妇的血清TNF-α、hCG水平进行测定,并采用受试者工作特征(receiver operating characteristic,ROC)曲线分析UtA-PI、UtA-RI、TNF-α、hCG单独及联合检测对孕妇凶险性前置胎盘合并胎盘植入的诊断价值。结果:观察组UtA-PI、UtA-RI水平明显低于对照组,差异有统计学意义(P<0.05)。观察组TNF-α、hCG水平均明显高于对照组,差异有统计学意义(P<0.05)。ROC曲线结果显示,UtA-PI、UtA-RI、TNF-α、hCG单独及联合检测诊断凶险性前置胎盘合并胎盘植入的曲线下面积(area under the curve,AUC)分别为0.812、0.816、0.957、0.833、0.992,诊断价值均较高,其中联合诊断价值最高。结论:采用UtA-PI、UtA-RI联合血清TNF-α、hCG检测可以提高对凶险性前置胎盘合并胎盘植入的诊断效能。
Objective:To explore the diagnostic value of uterine artery pulsation index(UtA-PI),uterine artery resistance index(UtA-RI)combined with serum tumor necrosis factor-α(TNF-α)and human chorionic gonadotropin(hCG)in dangerous placenta previa complicated with placenta implantation.Method:A total of 52 pregnant women diagnosed with dangerous placenta previa combined with placenta implantation in Yangchun People's Hospital from January 2020 to February 2022 were selected as the observation group,and 52 normal pregnant women who came to our hospital for healthy birth examination during the same period were selected as the control group.Uterine artery ultrasound was performed in all pregnant women,and UtA-PI and UtA-RI were recorded and compared between the two groups.Serum levels of TNF-αand hCG were measured by enzyme-linked immunoassay.In addition,receiver operating characteristic(ROC)curve was used to analyze the diagnostic value of UtA-PI,UtA-RI,TNF-αand hCG single and combined in pregnant women with dangerous placenta previa complicated with placenta implantation.Result:The levels of UtA-PI and UtA-RI in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of TNF-αand hCG in the observation group were significantly higher than those in the control group,the differences were statistically significant(P<0.05).ROC curve results showed that the area under the curve(AUC)of UtA-PI,UtA-RI,TNF-α,hCG and combined detection for the diagnosis of dangerous placenta previa complicated with placenta implantation were 0.812,0.816,0.957,0.833,0.992,respectively,with high diagnostic value,and the combined detection had the highest diagnostic value.Conclusion:UtA-PI,UtA-RI combined with serum TNF-αand hCG can improve the diagnostic efficacy of dangerous placenta previa complicated with placenta implantation.
作者
郭丽丽
阎光辉
GUO Lili;YAN Guanghui(Yangchun People's Hospital,Yangchun 529600,China;不详)
出处
《中外医学研究》
2024年第20期70-73,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
