摘要
目的 分析在重症支原体肺炎(Mycoplasma Pneumonia, MPP)患儿治疗中采取甲泼尼龙琥珀酸钠治疗对其疗效与炎症反应的影响。方法 选取2019年1月—2023年6月曹县人民医院普儿一科收治的62例重症MPP患儿,以随机数表法分组,观察组31例采取甲泼尼龙琥珀酸钠治疗,对照组31例采取常规治疗,比较两组临床疗效、临床症状改善时间、炎症因子水平。结果 观察组总有效率为93.6%,高于对照组(80.6%),差异有统计学意义(χ^(2)=7.381,P<0.05)。治疗后,观察组各项症状改善时间均比对照组更短,差异有统计学意义(P均<0.05)。治疗后,观察组各项炎症因子水平优于对照组,差异有统计学意义(P均<0.05)。结论 对重症MPP患儿采取甲泼尼龙琥珀酸钠治疗有较高治疗效果,还可显著缩短患儿临床症状改善时间,减轻炎症状态,较常规治疗更有助于促进患儿康复。
Objective To analyze the effect of methylprednisolone sodium succinate on the therapeutic effect and in-flammatory response of children with severe mycoplasma pneumonia(MPP).Methods A total of sixty-two children with severe MPP admitted to the Department of General Pediatrics I of Caoxian People's Hospital from January 2019 to June 2023 were selected.The children in the observation group(31 cases)were treated with methylprednisolone so-dium succinate,and the control group(31 cases)were treated with conventional treatment.The clinical efficacy,im-provement time of clinical symptoms and levels of inflammatory factors were compared between the two groups.Re-sults The total effective rate of the observation group was 93.6%,higher than that of the control group(80.6%),and the difference was statistically significant(χ^(2)=7.381,P<0.05).After treatment,the improvement time of symptoms in the observation group was shorter than that in the control group,and the difference was statistically significant(all P<0.05).After treatment,the levels of various inflammatory factors in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Methylprednisolone sodium succinate treatment for severe MPP children has a higher therapeutic effect,and can significantly shorten the improve-ment time of clinical symptoms and reduce inflammation,and is more conducive to promoting children rehabilitation than conventional treatment.
作者
孙文平
彭红梅
黄春彦
SUN Wenping;PENG Hongmei;HUANG Chunyan(The ward of general pediatrics I Caoxian People's Hospital,Heze,Shandong Province,274400 China)
出处
《系统医学》
2024年第11期123-126,共4页
Systems Medicine
关键词
甲泼尼龙琥珀酸钠
重症
支原体肺炎
炎症
Methylprednisolone sodium succinate
Severe case
MPP
Inflammation
