摘要
目的 分析早期局限性前列腺癌采取腹腔镜根治术的价值。方法 选取兰陵县人民医院于2021年7月—2023年7月收治的56例早期局限性前列腺癌患者为研究对象,采用随机抽签法分为开放组、腔镜组,各28例,开放组行开腹根治术,腔镜组行腹腔镜根治术,比较两组患者排尿情况、生化指标及安全性等。结果术后腔镜组残余尿量、充盈期膀胱顺应性值均低于开放组,最大尿流率高于开放组,差异有统计学意义(P均<0.05)。术后腔镜组胰岛素样生长因子-1、血管内皮生长因子以及前列腺特异性抗原等指标均低于开放组,差异有统计学意义(P均<0.05)。腔镜组手术、下床、出院时间均短于开放组,术中出血量低于开放组,差异有统计学意义(P均<0.05)。腔镜组并发症发生率为3.57%,低于开放组的25.00%,差异有统计学意义(χ^(2)=5.250,P<0.05)。结论 腹腔镜根治术安全性高,能预防各类并发症,纠正尿动力学水平,调节代谢状态,恢复血管功能,改善早期局限性前列腺癌预后。
Objective To analyze the value of laparoscopic radical resection for early localized prostate cancer.Meth-ods A total of fifty-six patients with early stage localized prostate cancer admitted to Lanling County People's Hospi-tal from July 2021 to July 2023 were selected as the study objects.They were divided into open group and endoscopic group by random drawing method,with twenty-eight cases in each group.Radical laparotomy was performed in the open group and laparoscopic radical laparotomy in the endoscopic group.Urinary status,biochemical indexes and safety were compared between the two groups.Results The residual urine volume and bladder compliance during fill-ing period in the endoscopic group were lower than those in the open group,and the maximum urine flow rate was higher than that in the open group,the difference were statistically significant(all P<0.05).The indexes of insulin-like growth factor-1,vascular endothelial growth factor and prostate-specific antigen in the endoscopic group were lower than those in the open group,the difference were statistically significant(all P<0.05).The time of operation,get-ting out of bed and discharge in the endoscopic group were shorter than those in the open group,and the amount of in-traoperative blood loss was lower than that in the open group,the difference were statistically significant(all P<0.05).The incidence of complications in the endoscopic group was 3.57%,lower than that in the open group(25.00%),the difference was statistically significant(χ^(2)=5.250,P<0.05).Conclusion Laparoscopic radical surgery has high safety,can prevent various complications,correct urodynamic level,regulate metabolic status,restore vascular function,and improve the prognosis of early localized prostate cancer.
作者
奈兰州
梁付真
钟家永
NAI Lanzhou;LIANG Fuzhen;ZHONG Jiayong(Department of Urology,Lanling County People's Hospital,Linyi,Shandong Province,277700 China)
出处
《系统医学》
2024年第11期98-101,共4页
Systems Medicine
关键词
腹腔镜根治术
排尿情况
安全性
局限性前列腺癌
Laparoscopic radical surgery
Urination status
Security
Localized prostate cancer
