摘要
目的:挖掘分析药浴文献方剂的核心用药规律,为人类非物质文化遗产藏医药浴临床应用及学术研究提供科学系统的数据支持。方法:选取《藏医药大典》(60本)等藏医药古籍文献为研究对象,搜集整理藏医药浴相关的有效数据元,运用SPSS Modeler18.0、SPSS Statistics 25.0、Gephi0.9.2软件采用描述统计、Apriori算法、聚类分析、复杂网络等方法,挖掘药浴方剂配伍规律。结果:在符合标准的409首方剂中,组方药物数量2~10味者占84%,按主要组方药物可分为五味甘露卡擦尔方与其他方剂两大类型;共涉及藏药材284味,其中坎巴、藏麻黄、秀巴等五味甘露组方药物频次及关联最高;聚类分析得出7种组合,疏经通络类、干黄水类、清热类、调和滋补类、消肿类、化脓类等不同功效结构的药对组合,可为不同证型用药提供参考。药物6味主要以甘、苦、辛,3化味以苦、甘,3性以凉、温居多,17效以钝、凉、重、糙等居多。主治功效以肿胀、白脉病等频次最高。结论:药浴方剂种类丰富、应用广泛,其中五味甘露卡擦尔方最常见,卡擦尔方体现了因人、因病施治的辨证论治原则,并挖掘出了多种常用药物组合及临床失传的方剂类型,对药浴临床应用及学术研究具有参考意义。
Objective:To explore and analyze the core medication rules of herbal bath literature prescriptions,to provide scientific and systematic data support for the clinical application and academic research of human intangible cultural heritage Tibetan medicinal bath.Methods:The effective data elements related to medical bathing were collected by selecting Tibetan medical Classics(60 copies) and other books as the objects.SPSS Modeler 18.0,SPSS Statistics 25.0,and Gephi0.9.2 software used descriptive statistics,Apriori algorithm,cluster analysis,complex network,and other methods to explore the compatibility rules of herbal bath prescription.Results:Among the 409 prescriptions that met the criteria,number of prescription drugs was 2~10,accounting for 84%.According to the main prescription drugs,it could be divided into two types:Five Flavor Manna Erel prescription and other prescriptions.284 Tibetan medicinal herbs were involved,among which Kamba,Tibetan Ephedra,and Xiuba had the highest frequency and correlation.Cluster analysis showed 7 kinds of drug combinations with different efficacy structures,such as dredging meridians and dredging collaterals,clearing damp,clearing heat,harmonizing and nourishing,reducing swelling,and suppurating,which provided the reference for drugs of different syndrome types.The six flavors of the medicine were mainly sweet,bitter and spicy.3 taste bitter,sweet;The 3 properties were mostly cool and warm,the 17 effects were dull,cool,heavy,and coarse.The most frequent indications were swelling and white pulse disease.Conclusion:Many kinds of herbal bath prescriptions are widely used,among which the Five Flavor Manna Kaser formula is the most common.Kaser formula embodies the principle of syndrome differentiation and treatment for people and diseases,and has unearthed a variety of common drug combinations and lost clinical prescription types,which has reference significance for the clinical application and academic research of herbal baths.
作者
夏刀才让
桑吉康卓
降拥四郎
王天虹
邹璟琳
泽翁拥忠
Xiadao Cairang;Sangji Kangzhuo;Jiangyong Silang;Wang Tianhong;Zou Jinglin;Zeweng Yongzhong(Ethnic Medicine School,Chengdu University of TCM,Chengdu 611137,China)
出处
《亚太传统医药》
2024年第4期162-168,共7页
Asia-Pacific Traditional Medicine
基金
四川省中医药管理局科学技术研究专项(2021MS017)
成都中医药大学“杏林学者”学科人才科研提升计划(QNXZ2020010)。
关键词
藏医药浴
五味甘露
方剂
组方规律
味性效
Tibetan Medicine Bath
Five Flavor Manna
Prescription
The Rule of Organization
Flavour,Character,Effect