摘要
探讨多不饱和脂肪酸(polyunsaturated fatty acid, PUFA)代谢产物在口腔疾病中的作用及应用研究进展。我们首先简要回顾了PUFA的代谢途径、关键酶,以及其生物学功能。接着,我们详细讨论了PUFA代谢产物在不同口腔疾病中的作用,包括口腔黏膜病、牙周病、牙体牙髓疾病、口腔癌和颞下颌关节紊乱等。研究表明,PUFA代谢产物在调控炎症、免疫反应和组织修复等方面具有重要作用,密切参与口腔疾病的发展和进展的进程。此外,PUFA代谢产物在诊断、治疗和预防口腔疾病方面也具有潜在应用价值。因此,对PUFA代谢产物在口腔疾病中的作用及应用的研究有助于深化对口腔疾病发病机制的认识,为口腔疾病的临床治疗提供新的思路和方法。
This review aims to explore research progress ofthe role and application of polyunsaturated fatty acid(PUFA) metabolites in oral diseases. We first briefly review the metabolic pathways and key enzymes of PUFAs, as well as their biological functions. Then, we discuss in detail the role of PUFA metabolites in various oral diseases, including oral mucosal diseases, periodontal diseases, dental and pulp diseases, oral cancer, and temporomandibular joint disorders(TMD). Studies have shown that PUFA metabolites play an important role in regulating inflammation, immune responses, and tissue repair, and are closely involved in the development and progression of oral diseases. Moreover, PUFA metabolites have potential application value in the diagnosis, treatment, and prevention of oral diseases. Therefore, research on the role and application of PUFA metabolites in oral diseases will help deepen our understanding of the pathogenesis of oral diseases and provide new ideas and methods for clinical treatment of oral diseases.
作者
徐华兴
韦晓玲
XU Huaxing;WEI Xiaoling(Department of Endodontics,Shanghai Stomatological Hospital,Shanghai 200001,China)
出处
《口腔医学》
CAS
2024年第7期545-550,共6页
Stomatology
基金
上海市口腔医院院级课题基金(SSH-2022-02)。
关键词
多不饱和脂肪酸
口腔疾病
牙周炎
牙髓炎
口腔黏膜病
p:olyunsaturated fatty acid
periodontitis
oral disease
pulpitis
oral mucosal diseases
