摘要
目的探讨经食道超声心动图对非瓣膜性房颤(NVAF)患者左心房血栓形成的评价结果,并分析血栓形成或自发性超声显影的影响因素。方法选取2019年1月至2022年1月于山东省聊城市第二人民医院进行经食道超声心动图检查的NVAF患者150例,根据是否发生左心房血栓形成或自发性超声显影,分为血栓组(32例)和无血栓组(118例)。收集两组患者的一般资料和心脏超声参数,经单因素及多因素Logistics回归分析NVAF患者发生左心房血栓形成的危险因素,绘制受试者工作特征曲线(ROC),分析其对NVAF患者左心房血栓形成的预测价值。结果与无血栓组比较,血栓组左心房前后径(LAAPD)水平较高,左心耳峰值血流排空速度(LAAV)、左心室射血分数(LVEF)和整体左心房长轴应变(GLALS)水平较低(P<0.05)。二元Logistics回归分析显示:LAAPD、LAAV、LVEF和GLALS是左心房血栓形成的影响因素(P<0.05)。绘制ROC曲线发现,LAAPD、LAAV、LVEF、GLALS以及联合预测左心房血栓形成的AUC依次为0.899、0.892、0.816、0.822和0.986,联合预测效能最高(P<0.05)。结论经食道超声心动图检测的LAAPD、LAAV、LVEF、GLALS是NVAF患者左心房血栓形成的影响因素,且对左心房血栓形成具有一定预测价值,尤其是联合预测效能最高。
Objective To investigate the efficacy of transesophageal echocardiography(TEE)for reviewing left atrial thrombosis,and analyze the influence factors for thrombosis and spontaneous echo contrast(SEC)in patients with non-valvular atrial fibrillation(NVAF).Methods NVAF patients(n=150)received TEE were chosen from the Second People's Hospital of Liaocheng City of Shandong Province from Jan.2019 to Jan.2022.The patients were divided,according to occurrence of left atrial thrombosis or SEC,into thrombus group(n=32)and non-thrombus group(n=118).The general material and parameters of cardiac uhrasonographywere collected in 2 groups.The risk factors for left atrial thrombosis were analyzed by using single-factor and multi-factor Logistics regression analysis in NVAF patients.The predictive value of receiver operating characteristic(ROC)curveto left atrial thrombosis was analyzed in NVAF patients.Results The levels of left atrial anteroposterior diameter(LAAPD)was higher,and levels of left atrial appendage peak flow emptying velocity(LAAV),left ventricular ejection fraction(LVEF)and global left atrial longitudinal strain(GLALS)were lower in thrombus group than those in non-thrombus group(P<0.05).The results of binary Logistics regression analysis showed that LAAPD,LAAV,LVEF and GLALS were influence factors for left atrial thrombosis(P<0.05).The results of ROC curve analysis showed that AUC of LAAPD,LAAV,LVEF,GLALS and combined prediction was,respectively,0.899,0.892,0.816,0.822 and 0.986 in predicting left atrial thrombosis(P<0.05).Conclusion LAAPD,LAAV,LVEF and GLALS detected by TEE are influence factors and have some predictive value to left atrial thrombosis,especially the combination prediction is the most effective in NVAF patients.
作者
潘新新
朱树来
韩晶晶
郭雷
Pan Xinxin;Zhu Shulai;Han Jingjing;Guo Lei(Department of Echocardiography,Second People's Hospital of Liaocheng City,Shandong Province,Liaocheng 252600,China;不详)
出处
《中国循证心血管医学杂志》
2024年第4期490-493,共4页
Chinese Journal of Evidence-Based Cardiovascular Medicine
关键词
经食道超声心动图
非瓣膜性房颤
左心房
自发性超声显影
Transesophageal echocardiography
Non-valvular atrial fibrillation
Left atrium
Spontaneous echo contrast
