摘要
目的探究在3.0TMR系统下,自旋锁定频率对心肌定量T1ρ值的影响。资料与方法前瞻性纳入2023年7—9月在安徽医科大学第一附属医院行心脏磁共振检查的38名健康志愿者。使用3.0TMR系统进行T1ρmapping及短轴电影成像扫描。获得自旋锁定频率为5Hz、300Hz、400Hz、500Hz的左心室短轴T1ρ图像,分别测得各节段T1ρ值和心肌纤维化指数,采用单因素重复测量方差分析观察不同自旋锁定频率下T1ρ值和心肌纤维化指数的差异。结果5 Hz、300 Hz、400 Hz、500 Hz的T1ρ值分别为(33.9±2.8)ms、(43.4±2.1)ms、(45.4±2.6)ms、(46.5±2.4)ms,自旋锁定频率越高,T1ρ值越大,且不同自旋锁定频率的T1ρ值之间差异有统计学意义(300 Hz比400 Hz:P<0.001;300 Hz比500 Hz:P<0.001;400 Hz比500 Hz:P=0.043)。300 Hz、400 Hz、500 Hz下的心肌纤维化指数分别为(9.4±2.2)ms、(11.3±2.9)ms、(12.6±2.7)ms,差异有统计学意义(300Hz比400Hz:P<0.001;300Hz比500Hz:P<0.001;400Hz比500Hz:P=0.033)。结论本研究提供了特定心脏磁共振设置下健康成人的心肌T1ρ值,结果表明自旋锁定频率可以影响T1ρ值。
Purpose To explore the influence of different spin-locking frequencies on T1ρvalues based on a 3.0T MR system.Materials and Methods Thirty-eight healthy adult volunteers underwent cardiac magnetic resonance imaging at the First Affiliated Hospital of Anhui Medical University from July to September 2023.T1ρmapping and short-axis cine imaging with steady-state free precession sequences were performed with 3.0T MR system.T1ρmapping sequence in three short-axis slices with three spin-lock frequencies at the amplitude of 5 Hz,300 Hz,400 Hz,and 500 Hz was scanned,respectively.T1ρrelaxation times and myocardial fibrosis index were quantified for each slice and each myocardial segment,the difference in T1ρof different spin-locking frequencies and myocardial fibrosis index was analyzed using one-way repeated-measures analysis of variance method.Results T1ρof 5 Hz,300 Hz,400 Hz,and 500 Hz were(33.9±2.8)ms,(43.4±2.1)ms,(45.4±2.6)ms and(46.5±2.4)ms,respectively;and T1ρvalues showed a significant progressive increase from the low spin-lock frequency to the high spin-lock frequency of the heart(300 Hz vs.400 Hz:P<0.001;300 Hz vs.500 Hz:P<0.001;400 Hz vs.500 Hz:P=0.043).In addition,the measured myocardial fibrosis index at 300 Hz,400 Hz and 500 Hz were(9.4±2.2)ms,(11.3±2.9)ms and(12.6±2.7)ms,respectively.Statistical analysis underscored significant variations among these measurements(300 Hz vs.400 Hz:P<0.001;300 Hz vs.500 Hz:P<0.001;400 Hz vs.500 Hz:P=0.033).Conclusion In this prospective study,myocardial T1ρvalues for the specific cardiac magnetic resonance setting are provided,and we found that spin-lock frequency can affect the T1ρvalues.
作者
韩彩云
邓炜
赵韧
束宏敏
王震
杨金秀
余永强
李小虎
HAN Caiyun;DENG Wei;ZHAO Ren;SHU Hongmin;WANG Zhen;YANG Jinxiu;YU Yongqiang;LI Xiaohu(Department of Radiology,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;不详)
出处
《中国医学影像学杂志》
CSCD
北大核心
2024年第7期731-735,共5页
Chinese Journal of Medical Imaging
基金
安徽省临床医学研究转化项目(202304295107020027,202304295107020028,202304295107020029)。
