摘要
目的观察穴位贴敷配合他达拉非治疗勃起功能障碍合并抑郁的临床疗效。方法将102例勃起功能障碍合并抑郁患者随机分为治疗组(52例)和对照组(50例)。治疗组采用穴位贴敷配合口服他达拉非治疗,对照组采用单纯口服他达拉非治疗。观察两组治疗前后国际勃起功能指数(the international index of erectile function-5,IIEF-5)评分、RigiScan AVSS各项监测数据(勃起总时间、根部≥60%勃起时间、头部≥60%勃起时间)及汉密尔顿抑郁量表(Hamiltondepression scale,HAMD)评分、健康状况调查问卷(36-itemshort-form,SF-36)评分的变化情况。比较两组临床疗效。结果治疗组总有效率为86.5%,明显高于对照组的74.0%(P<0.05)。两组治疗后IIFE-5评分、RigiScan AVSS各项监测数据均明显高于同组治疗前(P<0.05)。治疗组治疗后HAMD评分较同组治疗前显著下降,SF-36评分显著上升,差异均具有统计学意义(P<0.05);对照组治疗后仅SF-36评分较同组治疗前上升(P<0.05)。治疗组治疗后IIFE-5评分、RigiScan AVSS各项监测数据及SF-36评分均明显高于对照组,差异均有统计学意义(P<0.05)。结论穴位贴敷配合他达拉非是一种治疗勃起功能障碍合并抑郁的有效方法,能改善HAMD评分,提高患者生活质量。
Objective To observe the clinical efficacy of point application plus Tadalafil in treating erectile dysfunction complicated with depression.Method A total of 102 patients with erectile dysfunction complicated with depression were randomized into a treatment group of 52 cases and a control group of 50 cases.The treatment group was given point application and oral administration of Tadalafil,and the control group only took Tadalafil.The following outcome measures were observed before and after the treatment in both groups:the international index of erectile function-5(IIEF-5),RigiScan AVSS parameters(total tumescence time,basal rigidity≥60%tumescence time,and tip rigidity≥60%tumescence time),Hamilton depression scale(HAMD)score,and 36-item short-form healthy survey(SF-36)score.The clinical efficacy was also compared between the two groups.Result The total effective rate was 86.5%in the treatment group,significantly higher than 74.0%in the control group(P<0.05).After the treatment,both groups showed notable increases in the IIFE-5 score and RigiScan AVSS readings(P<0.05).The HAMD score dropped significantly,and the SF-36 score increased significantly in the treatment group(P<0.05);only the SF-36 score increased in the control group after the intervention(P<0.05).After the treatment,the treatment group significantly surpassed the control group in comparing the IIFE-5 score,RigiScan AVSS readings,and SF-36 score(P<0.05).Conclusion Point application plus Tadalafil is an effective approach for erectile dysfunction complicated with depression.This method can improve the HAMD score and enhance the patient’s quality of life.
作者
梁玉如
欧洋帆
徐潘
章洪
黄文彬
谢作钢
LIANG Yuru;OU Yangfan;XU Pan;ZHANG Hong;HUANG Wenbin;XIE Zuogang(Wenzhou Hospital of Integrated Chinese and Western Medicine,Wenzhou 325000,China)
出处
《上海针灸杂志》
CSCD
2024年第7期774-778,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
温州市中西医结合学会临床科研基金项目(2021011)
浙江省名老中医专家传承工作室建设项目(GZS2020042)。
关键词
勃起功能障碍
穴位贴敷法
抑郁
生活质量
汉密顿抑郁量表
Erectile dysfunction
Point application
Depression
Quality of life
Hamilton depression scale
