摘要
目的分析联合检测降钙素原(PCT)、D-二聚体(D-D)在肺栓塞与社区获得性肺炎鉴别诊断中的应用价值。方法观察性研究。抽取2022年6月至2023年6月郑州大学第一附属医院收治的56例肺栓塞患者和56例社区获得性肺炎患者,检测所有纳入患者的血清PCT、D-D水平。分析PCT、D-D及两者联合检测在肺栓塞、社区获得性肺炎鉴别诊断中的应用价值。结果肺栓塞患者血清PCT、D-D水平均高于社区获得性肺炎患者(P均<0.05)。Logistic回归分析检验结果显示,血清PCT、D-D水平高与肺栓塞有关(OR>1,P<0.05)。受试者工作特征曲线结果发现,血清PCT、D-D水平和两者联合鉴别肺栓塞、社区获得性肺炎的曲线下面积分别为0.907、0.931、0.984,均有一定诊断价值,且联合检测的价值更高,敏感度、特异度分别为0.946、0.929。结论联合检验PCT、D-D在肺栓塞、社区获得性肺炎鉴别诊断中的应用价值较高。
Objective To analyze the application value of combined testing of procalcitonin(PCT)and D-dimer(D-D)in the differential diagnosis of pulmonary embolism and community-acquired pneumonia.Methods Fifty-six patients with pulmonary embolism and 56 patients with community-acquired pneumonia admitted to the First Affiliated Hospital of Zhengzhou University from June 2022 to June 2023 were selected for the observational study.The serum levels of PCT and D-D in all patients were tested,and the application value of testing of PCT,D-D and combination of them in the differential diagnosis of pulmonary embolism and community-acquired pneumonia was analyzed.Results The serum levels of PCT and D-D in patients with pulmonary embolism were higher than those in patients with community-acquired pneumonia(all P<0.05).The results of logistic regression analysis showed that high expressions of serum PCT and D-D were associated with pulmonary embolism(OR>1,P<0.05).The results of the receiver operating characteristic curve showed that the areas under the curve for serum PCT level,D-D level,and combination of them in differentiation of pulmonary embolism and community-acquired pneumonia were 0.907,0.931,and 0.984,respectively,indicating certain diagnostic value.Moreover,the combined testing had higher value in the diagnosis,with sensitivity of 0.946 and specificity of 0.929.Conclusions The combined testing of PCT and D-D has high application value in the differential diagnosis of pulmonary embolism and community-acquired pneumonia.
作者
张凯
杨康丽
王红民
Zhang Kai;Yang Kangli;Wang Hongmin(Department of Respiratory,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《中国实用医刊》
2024年第11期71-74,共4页
Chinese Journal of Practical Medicine
关键词
肺栓塞
社区获得性肺炎
降钙素原
D二聚体
Pulmonary embolism
Community-acquired pneumonia
Procalcitonin
D-dimer
