摘要
目的探讨超声引导下微波消融技术治疗甲状腺良性结节的有效性和安全性。方法回顾性分析2016-2023年经病理证实符合纳入标准的甲状腺良性结节患者2913例3985个结节,评估一次性消融成功率、术后并发症及副作用的发生率。对其中中位随访时间12个月的1449例患者1890个消融结节,评估术后1、3、6、12、24个月及以上随访中结节的体积减少率(VRR)、复发率、再次消融率和技术有效消融率。结果所有患者一次性消融成功率为99.7%(3972/3985),技术有效消融率为88.6%(535/604),复发率为3.1%(59/1890),再次消融率为0.7%(13/1890)。术后1、3、6、12和24月及以上随访中结节VRR分别为(-17±430)%(n=727)、(48±152)%(n=643)、(72±38)%(n=573)、(83±20)%(n=604)、(88±18)%(n=279)。所有患者主要并发症的发生率为2.57%,次要并发症的发生率为2.06%,副作用的发生率为3.09%。结论超声引导下甲状腺结节微波消融是治疗甲状腺良性结节的有效和安全的方法。
Objective To evaluate the effectiveness and safety of ultrasound-guided microwave ablation technique in the treatment of benign thyroid nodules.Methods A total of 3985 nodules in 2913 patients with pathologically confirmed benign thyroid nodules during 2016-2023 were analyzed retrospectively.The one-time ablation success rate,incidence rate of postoperative complications and side effects were evaluated.For 1890 ablation nodules in 1449 patients with a median follow-up period of 12 months,the nodule volume reduction rate(VRR),recurrence rate,re-ablation rate and technical effective ablation rate were evaluated in postoperative 1,3,6,12,24 months and more.Results The success rate of one-time ablation in all patients was 99.7%(3972/3985),the technical effective ablation rate was 88.6%(535/604),the recurrence rate was 3.1%(59/1890)and the re-ablation rate was 0.7%(13/1890).In the follow-up nodules,VRR in postoperative 1,3,6,12,24 months and more was(-17±430)%(n=727),(48±152)%(n=643),(72±38)%(n=573),(83±20)%(n=604),(88±18)%(n=279),respectively.In all patients,the incidence rate of major complications was 2.57%,the incidence rate of minor complications was 2.06%,and the incidence of side effects was 3.09%.Conclusion Ultrasound-guided microwave ablation of thyroid nodules is an effective and safe method for the treatment of benign thyroid nodules.
作者
李超男
罗俊
陈吉东
周果
刘瑜妍
LI Chaonan;LUO Jun;CHEN Jidong;ZHOU Guo;LIU Yuyan(School of Medical and Life Sciences,Chengdu University of Traditional Chinese Medicine,Chengdu,Sichuan 611137,China;Department of Ultrasonography,Sichuan Provincial Academy of Medical Sciences/Sichuan Provincial People’s Hospital,Chengdu,Sichuan 610072,China)
出处
《重庆医学》
CAS
2024年第14期2110-2114,共5页
Chongqing medicine
基金
国家自然科学基金项目(61876158)。
关键词
超声
热消融
微波
甲状腺良性结节
ultrasound
thermal ablation
microwave
benign thyroid nodules
