摘要
目的回顾总结碳青霉烯类耐药肠杆菌(CRE)医院感染防控措施的最佳证据, 为医护人员进行CRE感染预防与控制提供循证参考。方法制订文献检索策略, 系统检索BMJ最佳临床实践、UpToDate、世界卫生组织、美国疾病控制与预防中心官网、欧洲疾病预防控制中心官网、国际指南协作网、美国国立实践技术指南库、英国国家卫生与临床优化研究所、加拿大安大略注册护士协会、医脉通、Cochrane Library、澳大利亚乔安娜布里格斯研究所循证卫生保健中心数据库、PubMed、Web of Science、中国知网、万方数据库、维普数据库、中国生物医学文献数据库中与CRE医院感染防控相关的证据, 检索时限为2018年1月1日至2023年10月1日。由2位研究成员独立进行文献质量评价, 对纳入的文献进行证据提取和综合。结果共纳入10篇文献, 包括6篇临床指南、3篇专家共识、1篇系统评价, 从预防监测、主动筛查、接触隔离、环境清洁消毒、细菌去定植、手卫生措施6个方面形成了29条最佳证据。结论本研究总结了CRE医院感染防控措施的最佳证据, 临床医护人员和管理部门应结合所在地CRE流行病学情况和资源要求, 采取积极有效的防控措施, 降低CRE感染的发生风险。
Objective To review and summarize the best evidence of prevention and control measures of carbapenem-resistant Enterobacteriaceae(CRE)hospital infection,and provide evidencebased reference for health care workers to prevent and control CRE infection.Methods A literature search strategy was developed to systematically search BMJ Best Clinical Practice,UpToDate,the World Health Organization,the Centers for Disease Control and Prevention website,the European Centers for Disease Control and Prevention website,the International Guidelines Collaboration website,the National Practice Technical Guidelines Library of the United States,the National Institute of Health and Clinical Optimization in the United Kingdom,the Ontario Medical Association of Canada,Maimai Tong,Cochrane Library,Australian Joanna Briggs Institute Evidence-Based Health Care Center database,PubMed,Web of Science,China National Knowledge Network,Wanfang database,VIP database,Chinese Biomedical Literature database of evidence related to the prevention and control of CRE hospital infection.The search period was from January 1,2018 to October 1,2023.The literature quality was evaluated independently by two research members,and evidence extraction and synthesis were carried out for the included literature.Results A total of 10 articles were included,including 6 guidelines,3 expert consensus articles,and 1 systematic review.29 best evidences were formed from 6 aspects:preventive monitoring,active screening,contact isolation,environmental cleaning and disinfection,bacterial colonization,and hand hygiene measures.Conclusions This study summarized the best evidence on the prevention and control measures of CRE infection in hospitals.Clinical staff and management departments should take active and effective prevention and control measures based on the local CRE epidemiological situation and resource requirements to reduce the risk of CRE infection.
作者
张海娇
王鸿伟
田芳英
丁永霞
Zhang Hajiao;Wang Hongwei;Tian Fangying;Ding Yongxia(Department of Infection Management,the Second Hospital of Shanxi Medical University,Taiyuan 030001,China;Department of Nursing,Shanxi Medical University,Taiyuan 030001,China)
出处
《中国实用护理杂志》
2024年第20期1574-1581,共8页
Chinese Journal of Practical Nursing
基金
山西省基础研究计划(202303021211121)
山西省软科学研究计划一般项目(2017041037-2)。
关键词
感染控制
医院感染
碳青霉烯类耐药肠杆菌
耐药性
证据总结
Infection control
Hospital infection
Carbapenem resistant Enterobacterium
Drug resistance
Summary of evidence
