摘要
目的:观察床旁支气管灌洗结合常规抗感染治疗对脑卒中吸入性肺炎患者血气指标及临床症状恢复情况的影响。方法:选取2021年1月—2022年1月南阳市第一人民医院ICU收治的112例脑卒中吸入性肺炎患者作为研究对象,采用抽签法将其分为常规组和试验组,每组各56例。常规组接受常规吸痰及抗感染药物治疗,试验组常规抗感染药物治疗基础上联合应用床旁支气管灌洗技术治疗,比较两组患者治疗前后的动脉血气指标、炎症指标改善情况以及临床症状缓解情况,对两组患者的预后情况进行综合评估。结果:治疗后,试验组患者血氧饱和度(SaO_(2))、动脉氧分压(PO_(2))高于常规组、动脉二氧化碳分压(PaCO_(2))低于常规组,差异有统计学意义(t=3.066、3.913、3.330,P<0.05);试验组患者白细胞计数(WBC)、中性粒细胞百分比(NE)、降钙素原(PCT)水平均低于常规组,差异有统计学意义(t=5.407、2.933、5.128,P<0.05);试验组患者咳嗽、咳痰缓解时间,退热时间,肺部湿啰音消失时间均低于常规组,差异有统计学意义(t=5.452、5.684、6.101、4.963,P<0.05);试验组患者ICU转出时间低于常规组、并发症发生率低于常规组,差异有统计学意义(t=5.861、χ^(2)=5.253,P<0.05)。结论:采用床旁支气管灌洗结合常规抗感染治疗可有效改善脑卒中吸入性肺炎的动脉血气指标及炎症指标,对促进患者症状恢复、加快病情改善、降低并发症发生风险均有意义。
Objective:To observe the effect of bedside bronchial lavage combined with routine anti-infection treatment on blood gas index and clinical symptom recovery of patients with stroke aspiration pneumonia.Methods:Taking 112 patients with stroke aspiration pneumonia admitted to ICU in the hospital from January 2021 to January 2022 as the study subjects.They were divided into the conventional group(56 cases)and the experimental group(56 cases)by the method of drawing lots.The conventional group was treated with conventional sputum aspiration and anti-infective drugs,and the experimental group was treated with bedside bronchial lavage technology on the basis of conventional anti-infective drugs.The arterial blood gas indexes before and after treatment were compared between the two groups.The improvement of inflammatory indicators and clinical symptoms were evaluated comprehensively.Results:After treatment,SaO_(2) and PO_(2) in the conventional group was higher than that in the conventional group,PaCO_(2) was lower than that in the conventional group,the differences were statistically significant(t=3.066,3.913,3.330;P<0.05).WBC,NE and PCT were lower than those of the conventional group,the differences were statistically significant(t=5.407,2.933,5.128;P<0.05).The cough relief time,expectoration elimination time,the fever elimination time and the lung moist rale elimination time were lower than those in the conventional group(t=5.452,5.684,6.101,4.963;P<0.05).The ICU transfer time and the complication rate were lower than those of the conventional group(t=5.861,χ^(2)=5.253;P<0.05).Conclusion:The use of bedside bronchial lavage combined with routine anti-infection treatment can effectively improve the arterial blood gas index and inflammation index of stroke aspiration pneumonia,and has effect in promoting the recovery of symptoms,accelerating the improvement of the condition and reducing the risk of complications.
作者
黄亚静
周婧
Huang Yajing;Zhou Jing(ICU,Nanyang First People’s Hospital,Nanyang,Henan,473000,China)
出处
《黑龙江医学》
2024年第14期1707-1709,1713,共4页
Heilongjiang Medical Journal
关键词
脑卒中吸入性肺炎
床旁支气管灌洗
抗感染治疗
血气指标
临床症状
Stroke aspiration pneumonia
Bedside bronchial lavage
Anti-infection treatment
Blood gas index
Clinical symptoms
