摘要
目的分析血清C反应蛋白(CRP)、同型半胱氨酸(Hcy)、脂联素联合检测对冠心病(CHD)介入治疗患者预后情况的预测价值。方法选取2021年7月至2022年7月在我院接受介入治疗的96例CHD患者纳入研究组,并选取同期在我院体检的110例健康者纳入对照组;治疗后随访1年,根据研究组预后情况分为预后不良组和预后良好组;比较研究组和对照组、预后良好组和预后不良组的血清CRP、Hcy、脂联素水平,并采用ROC曲线分析血清CRP、Hcy、脂联素联合检测对CHD介入治疗患者预后情况的预测价值。结果研究组血清CRP、Hcy、脂联素水平高于对照组(P<0.05)。预后不良组血清CRP、Hcy、脂联素水平高于预后良好组(P<0.05);ROC曲线结果显示,血清CRP、Hcy、脂联素联合检测预测CHD介入治疗患者预后的AUC为0.844,高于各指标单独检测(P<0.05)。结论血清CRP、Hcy、脂联素水平与CHD介入治疗患者预后情况关系密切,且血清CRP、Hcy及脂联素联合检测对CHD介入治疗患者预后情况的预测价值较高。
Objective To analyze the predictive value of combined detection of serum C-reactive protein(CRP),homocysteine(Hcy)and adiponectin on the prognosis of patients with coronary heart disease(CHD)undergoing interventional therapy.Methods 96 CHD patients undergoing interventional therapy in our hospital from July 2021 to July 2022 were selected as study group,and 110 healthy people with physical examination in our hospital during the same period were selected as control group.The study group was followed up for 1 year after treatrment,and divided into poor prognosis group and good prognosis group according to the prognosis.The serum CRP,Hcy and adiponectin levels were compared between the study group and the control group,and the good prognosis group and the poor prognosis group.ROC curve was used to analyze the predictive value of combined detection of serum CRP,Hcy and adiponectin on the prognosis of CHD patients undergoing interventional therapy.Results The serum CRP,Hcy and adiponectin levels of the study group were higher than those of the control group(P<0.05).The serum CRP,Hcy and adiponectin levels of the poor prognosis group were higher than those of the good prognosis group(P<0.05).ROC curve results showed that the AUC of combined detection of serum CRP,Hcy and adiponectin in predicting the prognosis of CHD patients undergoing interventional therapy was 0.844,higher than that of each index alone(P<0.05).Conclusions The serum CRP,Hcy and adiponectin levels are closely related to the prognosis of CHD patients undergoing interventional therapy,and the combined detection of serum CRP,Hcy and adiponectin has higher predictive value on the prognosis of CHD patients undergoing interventional therapy.
作者
田婵玙
刘宁宁
TIAN Chanyu;LIU Ningning(Clinical Laboratory,the Fifth Clinical Medical College of Henan University of Traditional Chinese Medicine/Zhengzhou People's Hospital,Zhengzhou 450003,China)
出处
《临床医学工程》
2024年第7期837-838,共2页
Clinical Medicine & Engineering
关键词
冠心病
介入治疗
CRP
HCY
脂联素
预测价值
Coronary heart disease
Interventional therapy
CRP
Hcy
Adiponectin
Predictive value
