期刊文献+

手足口病疫苗的真实世界研究

Real-world study of hand,foot and mouth disease vaccine
原文传递
导出
摘要 手足口病(hand,foot and mouth disease,HFMD)是一种儿童常见传染病,已成为全球范围内特别是亚太地区的重大公共卫生问题之一,严重影响儿童健康,给家庭和社会造成了严重的疾病负担。全球现有3种HFMD疫苗(均为EV71灭活疫苗),于2016年先后在中国上市。上市后的真实世界研究显示,EV71相关的HFMD发病率、重症和死亡人数开始下降,表现出良好的保护效果,且数据显示疫苗后时代我国HFMD病原谱发生显著变化。本文旨在对EV71疫苗上市后的真实世界研究进行综述。 Hand,foot and mouth disease(HFMD)is a common infectious disease among children,and has emerged as a substantial global public health concern,particularly in the Asia-Pacific region.It has a serious impact on children′s health and imposes a significant disease burden on families and society.Currently,there are three globally available HFMD vaccines(all of them are EV71 inactivated vaccine),which were first approved and marketed in China in 2016.Real-world studies have shown a decrease in the incidence,severity,and mortality rate of EV71-related HFMD,providing evidence of its effectiveness.Additionally,related data have indicated a significant change in the pathogen spectrum of HFMD in China in the post-vaccine era.This article aims to provide a comprehensive review of the safety,effectiveness and immune-persistence data of EV71 vaccine acquired through real-world studies.
作者 廖梦俊 邱凌娴 陈璐 黄悦 黄守杰 程通 吴婷 Liao Mengjun;Qiu Lingxian;Chen Lu;Huang Yue;Huang Shoujie;Cheng Tong;Wu Ting(State Key Laboratory of Vaccines for Infectious Diseases,Xiang An Biomedicine Laboratory,School of Public Health,Xiamen University,Xiamen 361102,China)
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2024年第6期553-559,共7页 Chinese Journal of Microbiology and Immunology
基金 国家自然科学基金(82072282,82272310)。
关键词 手足口病 EV71疫苗 流行病学特征 真实世界研究 Hand,foot and mouth disease EV71 vaccine Epidemiological characteristics Real-world study
  • 相关文献

参考文献5

二级参考文献84

共引文献173

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部