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飞行人员频发早搏治愈后在低压缺氧环境下的心血管功能评价研究

A study on cardiovascular function evaluation of frequent premature contractions in pilots after being cured in a hypobaric hypoxic environment
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摘要 目的在模拟低压缺氧环境下,对经过治疗的频发早搏患病飞行人员进行心血管功能评价,从而为其治愈后的安全放飞提供充分理论依据。方法采用低压舱模拟5000 m海拔低压缺氧环境,运用动态心电、动态血压、心理运动能力测试及心率变异性分析等设备,监测飞行人员在低压缺氧环境下的异常心律、血压波动、模拟飞行操作能力及心率变异性等指标。结果低压缺氧环境暴露条件下,6例频发早搏治愈飞行人员的模拟飞行能力未受显著影响;房早和室早的发生次数及占比无明显增加;收缩压、舒张压、脉压差和平均动脉压与地面海拔高度的监测指标相比无显著变化;心率变异性分析表明:与上舱前比,频发早搏治愈飞行人员在5000 m低压缺氧环境中的极低频(VLF)显著增加(P<0.05),自主神经平衡能力(ANS平衡)明显降低(P<0.05),其余指标无显著差异;此外,5000 m低压缺氧环境可导致受试者的血氧饱和度明显降低,但仍在正常耐受范围,受试者均未出现心悸、头晕等不适症状。结论对频发早搏治愈飞行人员在低压缺氧环境下的心血管功能进行评价,可为精准化航空医学鉴定和飞行安全性评估提供参考依据。 AIM To evaluate the cardiovascular function of pilots with frequent premature contractions(PCs)who have undergone treatment in a hypobaric hypoxic environment,in order to provide sufficient theoretical basis for their flight safety decisions after treatment.METHODS Simulate hypobaric hypoxic environment at an altitude of 5000-meter using a low-pressure chamber,and monitor arrhythmia,blood pressure fluctuations,simulated flight maneuverability,and heart rate variability of pilots in hypobaric hypoxic environment using equipment such as dynamic electrocardiogram,dynamic blood pressure,psychomotor ability testing,and heart rate variability analysis.RESULTS The simulated flight ability of 6 patients was not significantly affected by to hypobaric hypoxic environment;There was no significant increase in the frequency and proportion of premature atrial and ventricular contractions;The changes in systolic blood pressure,diastolic blood pressure,pulse pressure difference,and mean arterial pressure were not significant compared to normal conditions;The analysis of heart rate variability showed that compared to normal conditions,the patient's extremely low frequency(VLF)significantly increased(P<0.05),and the autonomic nervous system balance ability(ANS balance)significantly decreased(P<0.05),with no significant difference in other indicators;In a hypobaric hypoxic environment of 5000-meter,the patient's blood oxygen saturation significantly decreased,but it was still within the normal tolerance range,and no discomfort symptoms such as dizziness appeared in the subjects.CONCLUSION Evaluating the cardiovascular function of pilots after frequent PCs are cured in a hypobaric hypoxic environment can provide a reference basis for precise aviation medical evaluation and flight safety assessment.
作者 刘峰舟 李亚娟 万群 杨倩 赵梓彤 王小成 薛军辉 郑建勇 王瀚 LIU Feng-zhou;LI Ya-juan;WAN Qun;YANG Qian;ZHAO Zi-tong;WANG Xiao-cheng;XUE Jun-hui;ZHENG Jian-yong;WANG Han(Center of Aerospace Clinical Medical,School of Aviation and Aerospace Medicine,First Affiliated Hospital,Air Force Medical University,Xi'an 710032,Shaanxi,China;Department of Aviation Medicine,First Affiliated Hospital,Air Force Medical University,Xi'an 710032,Shaanxi,China)
出处 《心脏杂志》 CAS 2024年第4期427-432,共6页 Chinese Heart Journal
基金 空军军医大学第一附属医院军事医学临床应用面上项目(JSYXM17) 空军军医大学后勤科研保健专项(23KYBJ01)。
关键词 飞行人员 心律失常 低压缺氧 飞行安全 航空医学鉴定 flight personnel arrhythmias hypobaric hypoxia flight safety medical evaluation
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