摘要
目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)干预对合并视网膜分支静脉阻塞(BRVO)疗效的影响。方法选取2020年6月至2021年12月收治的202例BRVO合并OSAHS,采用随机数字表法分为观察组101例和对照组101例,对照组给予BRVO规范治疗,观察组给予BRVO规范治疗与生活方式干预(饮食指导及体位疗法),统计比较2组入组时及入组后1个月、6个月、1年、1.5年夜间平均动脉血氧饱和度(MSaO_(2))、最低动脉血氧饱和度(LSaO_(2))、氧减指数(ODI)及最佳矫正视力、黄斑中心凹视网膜厚度(CRT)和视网膜中央动脉(CRA)舒张末期血流速度(EDV)、收缩期峰值流速(PSV),以及入组后1.5年内2组并发症累计发生率和累计实施手术率。结果观察组并发症累计发生率(13.54%)、累计实施手术率(8.33%)较对照组(26.97%、19.10%)低(P<0.05)。入组后1个月、6个月、1年、1.5年观察组夜间MSaO_(2)、LSaO_(2)及CRA的PSV、EDV均高于对照组,夜间ODI、最佳矫正视力、CRT均低于对照组(P<0.05,P<0.01)。结论在BRVO治疗的同时给予OSAHS干预有利于促进BRVO合并OSAHS病情恢复。
Objective To investigate the effect of intervention for obstructive sleep apnea hypopnea syndrome(OSAHS)on the efficacy of combined branch retinal vein obstruction(BRVO).Methods A total of 202 patients with BRVO complicated with OSAHS treated from June 2020 to December 2021 were selected and divided into observation group(n=101)and control group(n=101)by random number table method.The control group was given BRVO standard treatment,and the observation group was given BRVO standard treatment and lifestyle intervention(dietary guidance and posture therapy).The mean arterial oxygen saturation(MSaO_(2))during night time,lowest arterial oxygen saturation(LSaO_(2)),oxygen desaturation index(ODI),best corrected visual acuity(BCVA),macular foveal retinal thickness(CRT),central retinal artery(CRA)end-diastolic blood flow velocity(EDV),peak systolic flow velocity(PSV)between the two groups at the time of enrollment and at 1 month,6 months,1 year and 1.5 years after enrollment,as well as the cumulative incidence of complications and the cumula-tive rate of operation performed in the two groups within 1.5 years after enrollment,were statistically compared.Results The cumulative incidence of complication(13.54%)and cumulative rate of operation(8.33%)in the observation group were lower than those in the control group(26.97%,19.10%)(P<0.05).At 1 month,6 months,1 year and 1.5 years after admission,PSV and EDV of MSaO_(2),LSaO,during night time and CRA in observation group were higher than those in control group,while ODI during night time,BCVA and CRT were lower than those in control group(P<0.05,P<0.01).Conclusion Intervention for OSAHS during BRVO treatment can promote the recovery of BRVO combined with OSAHS.
作者
崔明霞
树玲博
李楠
段颖
张阳
刘晓哲
任国英
CUI Mingxia;SHU Lingbo;LI Nan;DUAN Ying;ZHANG Yang;LIU Xiaozhe;REN Guoying(Department of Ophthalmology,the Fourth People's Hospital of Hengshui City,Hengshui,Hebei 053000,China;Department of Ultrasound,the Fourth People's Hospital of Hengshui City,Hengshui,Hebei 053000,China;Department of ENT-Head and Neck Surgery,the Fourth People's Hospital of Hengshui City,Hengshui,Hebei 053000,China;Department of Ophthalmology,Gucheng County Hospital,Gucheng,Hebei 253899,China)
出处
《临床误诊误治》
CAS
2024年第11期89-94,共6页
Clinical Misdiagnosis & Mistherapy
基金
衡水市重点研发计划项目(2023014067Z)。
