摘要
目的:分析浆细胞性乳腺炎(PCM)患者应用疏肝理气、清热解毒法对其术后恢复及免疫因子的影响。方法:选取PCM术后患者88例,以随机方式分为两组。对照组采用常规西医疗法,研究组在对照组基础上应用中药疏肝理气、清热解毒法治疗,比较两组患者恢复情况、免疫因子指标变化及不良反应、并发症发生情况。结果:研究组治疗总有效率高于对照组(P<0.05)。与对照组比较,研究组的术后引流时间、拆线时间、切口愈合时间、住院时间更短(P<0.05)。两组换药时间比较,差异无统计学意义(P>0.05)。两组术后当天疼痛视觉模拟评分(VAS)比较,差异无统计学意义(P>0.05)。研究组术后3 d及术后7 d的VAS评分低于对照组,差异有统计学意义(均P<0.05)。与对照组比较,研究组术后7 d的血清分化簇3(CD3^(+))、分化簇4(CD4^(+))、CD4^(+)/分化簇8(CD8^(+))CD8^(+)更高,而CD8^(+)更低,差异有统计学意义(均P<0.05)。两组不良反应、并发症发生率比较,差异无统计学意义(均P>0.05)。结论:对PCM术后患者应用中药疏肝理气、清热解毒法较单纯西药治疗更利于促进患者恢复,减轻疼痛,促进免疫功能恢复,且安全性较好。
Objective:To analyze effects of Shugan Liqi,Qingre Jiedu on recovery and immune factors in patients with plasma cell mastitis(PCM)after operation.Methods:88 patients with PCM were randomly divided into two groups.The control group received conventional western medicine therapy.On the basis of the control group,the study group were treated with traditional Chinese medicine Shugan Liqi,Qingre Jiedu.The recovery,changes of immune factors and occurrence of adverse reactions complications were compared between the two groups.Results:The effective rate of the study group was higher than that in the control group(P<0.05).Compared with the control group,the postoperative drainage time,suture removal time,incision healing time and hospital stay in the study group were shorter(P<0.05).There was no significant difference in dressing change time between the two groups(P>0.05).There was no significant difference in visual analogue scale(VAS)between the two groups on the day after surgery(P>0.05).The VAS scores of the study group were lower at 3 and 7 days after surgery(P<0.05).Serum differentiation cluster 3(CD3^(+)),differentiation cluster 4(CD4^(+)),CD4^(+)/differentiation cluster 8(CD8^(+))were higher and CD8^(+)were lower in the study group 7 days after surgery.There was no significant difference in the incidence of adverse reactions complications between the two groups(P>0.05).Conclusion:Compared with western medicine alone,the application of TCM Shugan Liqi and Qingre Jiedu in patients with PCM after operation were more beneficial to promote recovery of patients,relieve pain and promote recovery of immune functionand better safety.
作者
刘晓青
任伊宁
兴伟
周伟
LIU Xiaoqing;REN Yining;XING Wei;ZHOU Wei(Department of General Surgery,First Affiliated Hospital of Hebei University of Chinese Medicine,Shijiazhuang 050011,China)
出处
《陕西中医》
CAS
2024年第7期926-929,共4页
Shaanxi Journal of Traditional Chinese Medicine
基金
河北省中医药管理局科研计划项目(2023043)。
关键词
浆细胞性乳腺炎
乳痈
疏肝理气
清热解毒
免疫因子
分化簇3
分化簇4
Plasma cell mastitis
Ruyong
Shugan Liqi
Qingre Jiedu
Immune factor
Differentiation cluster 3
Differentiation cluster 4
