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不同浸润程度肺腺癌患者应用高分辨CT检测肺内磨玻璃密度结节及胸膜凹陷征和支气管阳性征的临床意义分析

Clinical significance of computed tomography groundglass opacity,pleural indentation sign and bronchial positive sign by high resolution CT in patients with different invasion degree of lung adenocarcinoma
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摘要 目的探讨不同浸润程度肺腺癌患者应用高分辨CT(HRCT)检测肺内磨玻璃密度结节(CTGGO)及胸膜凹陷征、支气管阳性征的效果,分析HRCT对不同浸润程度肺腺癌的诊断价值。方法选取2021年7月至2022年7月瑞金市人民医院收治的80例肺腺癌(病理侵袭性)患者作为病理侵袭性组,随机选取同期80例肺腺癌(病理非侵袭性)患者作为病理非侵袭性组,所有患者均行HRCT检查。根据2015年WHO制定的《肺腺癌新分类》,将肺腺癌(病理侵袭性)患者分为浸润前病变(PI)、微浸润性腺癌(MIA)和浸润性腺癌(IA)。比较两组与病理侵袭性组不同浸润程度肺腺癌患者CTGGO、胸膜凹陷征、支气管阳性征占比情况及双侧肺部不同大小病灶的检出率。结果病理侵袭性组CTGGO、胸膜凹陷征、支气管阳性征占比均高于病理非侵袭性组(P<0.05)。病理侵袭性组双侧肺部不同大小病灶总检出率为93.75%,病理非侵袭性组为86.25%,两组比较差异无统计学意义。不同浸润程度肺腺癌患者CTGGO及胸膜凹陷征、支气管阳性征占比比较差异有统计学意义(P<0.05);IA患者CTGGO、支气管阳性征均低于PI患者,胸膜凹陷征、支气管阳性征均低于MIA患者,MIA患者CTGGO占比低于PI患者,差异有统计学意义(P<0.05)。病理侵袭性组PI、MIA、IA患者0~5、>5~10、>10~15、>15~20 mm病灶检出率比较差异无统计学意义。结论HRCT征象可应用于不同浸润程度的肺腺癌患者,通过HRCT图像中的CTGGO、胸膜凹陷征和支气管阳性征,进一步诊断肺腺癌。 Objective To explore the detection effect of high resolution CT(HRCT)on computed tomography ground-glass opacity(CTGGO),pleural indentation sign and bronchial positive sign,and to analyze the diagnostic value of HRCT in patients with different invasion degree of lung adenocarcinoma.Methods A total of 80 patients with lung adenocarcinoma(pathological invasion)and 80 patients with lung adenocarcinoma(pathological non-invasion)during same period in Ruijin People's Hospital from July 2021 and July 2022 were enrolled as the pathological invasion group and the pathological non-invasion group,all patients underwent HRCT examination.The patients in the pathological invasion group were divided into the pre-invasion lesion(PI),minimally invasive adenocarcinoma(MIA)and the invasive adenocarcinoma(IA)according to New Classification of Lung Adenocarcinoma formulated by WHO in 2015.The proportions of CTGGO,pleural indentation sign and bronchial positive sign,and the detection rates of different sizes of bilateral lung lesions were compared between the two groups and patients with lung adenocarcinoma with different degrees of infiltration in the pathological invasion group.Results The proportions of CTGGO,pleural indentation sign and bronchial positive sign in the pathological invasion group were higher than those in the pathological non-invasion group(P<0.05).The total detection rate of bilateral lung lesions of different sizes in the pathological invasion group was 93.75%,and that in the pathological non-invasion group was 86.25%,there was no significant difference between the two groups.There were statistically significant differences in the proportion of CTGGO,pleural indentation sign and bronchial positive sign in patients with different degrees of invasion of lung adenocarcinoma(P<0.05);CTGGO and bronchial positive signs in IA patients were lower than those in PI patients,pleural indentation and bronchial positive signs were lower than those in MIA patients,and the proportion of CTGGO in MIA patients was lower than that i
作者 邹志刚 刘晓辉 邓煜 ZOU Zhigang;LIU Xiaohui;DENG Yu(CT/MRI Room,Ruijin People's Hospital,Ganzhou,Jiangxi,342500,China)
出处 《当代医学》 2024年第10期117-121,共5页 Contemporary Medicine
关键词 肺腺癌 高分辨CT 肺内磨玻璃密度结节 胸膜凹陷征 支气管阳性征 Lung adenocarcinoma High resolution CT Computed tomography ground-glass opacity Pleural indentation sign Bronchial positive sign
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