摘要
目的:比较海奥口腔生物膜单独或联合同种异体骨对颌骨囊肿术后骨缺损的修复效果。方法:选择2020年11月—2022年7月入住江南大学附属医院的颌骨囊肿术后骨缺损患者105例进行前瞻性研究。按随机数字表法将患者分为海奥膜组、异体骨组和联合组。其中,海奥膜组(35例)使用海奥口腔生物膜,异体骨组(35例)使用同种异体骨,联合组(35例)联合使用海奥口腔生物膜和同种异体骨。观察并比较3组患者的临床基本资料、切口处愈合疗效、骨缺损处的骨密度、骨吸收量、附着丧失情况。采用SPSS 22.0软件包对数据进行统计学分析。结果:3组患者一般临床资料无显著差异(P>0.05)。联合组术后牙龈软组织形态恢复效果显著优于海奥膜组和异体骨组(P<0.05)。术前,3组患者骨缺损处骨密度无显著差异(P>0.05);术后6个月和12个月,3组骨密度显著改善(P<0.05),且联合组骨密度显著高于海奥膜组和异体骨组(P<0.05)。术前,3组患者垂直骨吸收量和舌侧骨吸收量无显著差异(P>0.05)。术后6个月和12个月,3组垂直骨吸收量和舌侧骨吸收量显著降低(P<0.05);联合组显著小于海奥膜组和异体骨组(P<0.05)。术前,3组患者附着丧失无显著差异(P>0.05)。术后6个月和12个月,3组附着丧失减小(P<0.05);联合组显著小于海奥膜组和异体骨组(P<0.05)。结论:海奥口腔生物膜联合同种异体骨治疗颌骨囊肿术后骨缺损疗效良好,有利于牙龈软组织恢复,改善骨密度,减少骨吸收量和附着丧失。
PURPOSE:To compare the repair effects of Haiao oral biofilm alone or in combination with allogeneic bone graft on bone defects after jaw bone cyst surgery.METHODS:A prospective study was conducted on 105 patients with bone defects after jaw bone cyst surgery who were admitted to Affiliated Hospital of Jiangnan University from November 2020 to July 2022.According to the random number table methods,the patients were divided into three groups:Haiao membrane group,allogeneic bone graft group and combination group.Among them,Haiao membrane group(35 patients)were repaired using Haiao oral biofilm;allogeneic bone group(35 patients)using allogeneic bone,while combined group(35 patients)using a combination of Haiao oral biofilm and allogeneic bone graft.The clinical basic data of three groups of patients were compared,including the healing effect at the incision,bone density at the bone defect,bone resorption and attachment loss.Statistical analysis was performed with SPSS 22.0 software package.RESULTS:There was no significant difference in general clinical data among the three groups(P>0.05).The postoperative restoration effect of gingival soft tissue morphology in combined group was significantly better than that in Haiao membrane group and allogeneic bone graft group(P<0.05).There was no significant difference in bone density at the bone defect site among the three groups before treatment(P>0.05);6 and 12 months after treatment,the bone density of the three groups was significantly improved(P<0.05),and combined group was significantly higher than the other groups(P<0.05).There was no significant difference in the vertical and lingual bone resorption levels among the three groups before treatment(P>0.05);6 and 12 months after treatment,the vertical and lingual bone resorption levels of the three groups were significantly reduced(P<0.05),and combined group were significantly lower than the other groups(P<0.05).There was no significant difference in attachment loss among the three groups before treatment(P>0.05);6 and 12
作者
魏子程
周晨
季炼
侯德强
董煜
WEI Zi-cheng;ZHOU Chen;JI Lian;HOU De-qiang;DONG Yu(Department of Stomatology,Affiliated Hospital of Jiangnan University.Wuxi 241062,Jiangsu Province,China)
出处
《上海口腔医学》
CAS
2024年第3期285-289,共5页
Shanghai Journal of Stomatology
基金
无锡市青年医学重点人才培养(QNRC058)。
