摘要
建立干式灰化-电感耦合等离子质谱仪(ICP-MS)测定塑料输液容器中铜(Cu)、镉(Cd)、铬(Cr)、铅(Pb)、钡(Ba)、铝(Al)、钛(Ti)、镁(Mg)、镍(Ni)、钼(Mo)、钴(Co)、钒(V)12种元素含量的方法。经干式灰化法处理样品制备供试液,采用电感耦合等离子质谱法(ICP-MS),同时测定塑料输液容器中的12种金属元素。结果显示,12种金属元素在0.001μg/m L~0.100μg/m L范围内,具有良好线性关系,相关系数R>0.999,方法检出限为0.000 2μg/g~0.084 0μg/g,精密度RSD为0.5%~3.4%,平均回收率为87.5%~110.2%,重复性RSD为3.1%~10.0%。本方法灵敏度高,回收率、重复性较好,可用于测定塑料输液容器中12种金属元素。
To establish a dry ashing-ICP-MS method for the determination of Cu,Cd,Cr,Pb,Ba,Al,Ti,Mg,Ni,Mo,Co,and V in plastic infusion containers.The samples was treated with dry ashing method to prepare the test solution,then simultaneously determined these 12 metal elements in plastic infusion containers by ICP-MS.The results showed that the 12 metal elements had a good linear relationshipin the range of 0.001μg/mL-0.100μg/mL,the correlation coefficient was greater than 0.999.Method detection limit was 0.0002μg/g-0.0840μg/g.The relative standard deviation of precision was 0.5%-3.4%.Average recovery rate was 87.5%-110.2%.The relative standard deviation of repeatability was 3.1%-10.0%.This method is sensitive,efficient and accurate,so it can be used to determine Simultaneously these 12 metal elements in plastic infusion containers.
作者
刘磅
刘园园
黄海萍
颜敏
罗洁
张珏
LIU Pang;LIU Yuanyuan;HUANG Haiping;YAN Min;LUO Jie;ZHANG Jue(Hunan Institute for Drug Control,Changsha Hunan,410010,China)
出处
《质量安全与检验检测》
2024年第3期1-5,共5页
QUALITY SAFETY INSPECTION AND TESTING
关键词
塑料输液容器
电感耦合等离子质谱仪
金属元素
干式灰化
Plastic infusion container
Inductively coupled plasma mass spectrometry
Metal element
Dry ashing
