摘要
目的研究促甲状腺激素(TSH)及甲状腺自身抗体与分化型甲状腺癌(DTC)的关系。方法选择本院2022年1月-2022年12月收治100例甲状腺结节患者,根据“术后病理学结果”分良性组(良性甲状腺结节),恶性组(DTC患者)各50例,均行TSH、甲状腺自身抗体检测,检测结果分析。结果两组比较TPOAb指标无差异,P>0.05;较良性组,恶性组TSH、TgAb指标更高;恶性组TSH增高异常率(20.00%)高于良性组(8.00%);恶性组TgAb阳性率(16.00%)高于良性组(4.00%),χ^(2)=11.259,6.327;导致DTC疾病独立危险因素是TSH增高、TgAb阳性,P<0.05(具有统计学意义)。结论TSH增高、TgAb阳性是造成DTC疾病的独立危险因素,对疾病鉴别诊断有一定价值,为后期诊疗提供数据支持、改善预后,值得推崇。
Objective To investigate the relationship between thyroid thyroid-stimulating hormone(TSH),thyroid autoantibodies and differentiated thyroid cancer(DTC).Methods A total of 100 Thyroid nodule patients from January 2022 to December 2022 were selected and divided into control group(benign Thyroid nodule)according to“Postoperative pathological results”,observation Group(DTC patients)50 cases,all TSH,thyroid autoantibody detection,detection results analysis.Results There was no significant difference in TPOAB between the two groups(P>0.05),TSH and TgAb were higher in the observation group(20.00%)than in the control group(8.00%)The positive rate of TgAb in the observation group(16.00%)was higher than that in the control group(4.00%),χ^(2)=11.259,6.327.The independent risk factors of DTC were the increase of TSH and the positive rate of TgAb,P<0.05(with statistical significance).Conclusion Increased TSH and positive TGAB are the independent risk factors of DTC,which are valuable for differential diagnosis,providing data for later diagnosis and treatment,and improving prognosis.
作者
何聿波
史松槟
李奇功
张国祥
He Yubo;Shi Songbing;Li Qigong;Zhang Guoxiang(Siyang Hospital,Suqian,Jiangsu,223700)
出处
《中国医学文摘（耳鼻咽喉科学）》
2024年第3期28-30,共3页
Chinese Medical Digest(Otorhinolaryngology)
关键词
促甲状腺激素
甲状腺自身抗体
分化型甲状腺癌
检测结果
Thyroid-stimulating hormone
Thyroid autoantibodies
Differentiated thyroid cancer
Test results
