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鼻息肉内镜术后应用糠酸莫米松喷剂预防复发的效果观察

Effect of Mometasone furoate spray on preventing recurrence of nasal polyp after endoscopic surgery
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摘要 目的讨论鼻息肉内镜术后应用糠酸莫米松喷剂预防复发的效果。方法2021年7月-2023年7月,前瞻性选取76例鼻息肉内镜术后患者,随机分为对照组38例与研究组38例。对照组内镜术后予以鼻腔冲洗治疗,研究组在对照组基础上予以糠酸莫米松喷剂,共连续性行各自治疗方案3个月,并观察康复效果、鼻腔症状、不良事件与病情复发机率。结果研究组术后3个月康复总有效率的97.37%较对照组的84.42%更高,P<0.05。研究组术后3个月阶段时鼻腔清洁度、鼻黏膜水肿或充血、鼻黏膜增生较对照组更低,P<0.05。研究组术后3个月鼻腔粘连、鼻腔干燥发生率发生率较对照组更低,P<0.05。研究组术后3个月无复发,明显低于对照组术后3个月复发率的13.16%,P<0.05。结论鼻息肉内镜术后应用糠酸莫米松喷剂可提高康复效果,促使鼻腔症状消退,降低风险事件与复发机率。 Objective To observe the effect of Mometasone furoate spray on preventing recurrence of nasal polyps after endoscopic surgery.Methods From July 2021 to July 2023,76 patients with endoscopic nasal polyps were prospectively selected and randomly divided into control group(38 cases)and study group(38 cases).The control group was given nasal irrigation treatment after endoscopic surgery,and the study group was given mometasone furoate spray on the basis of the control group.The treatment plan was continued for a total of 3 months,and the recovery effect,nasal symptoms,adverse events and the recurrence rate of the disease were observed.Results The total effective rate was 97.37%in the study group and 84.42%in the control group(P<0.05).Nasal cleanliness,edema or congestion of nasal mucosa and hyperplasia of nasal mucosa in the study group were lower than those in the control group at 3 months after operation(P<0.05).The incidence of nasal adhesion and nasal dryness in the study group was lower than that in the control group 3 months after operation(P<0.05).There was no recurrence 3 months after operation in the study group,which was significantly lower than that in the control group(13.16%),P<0.05.Conclusion The application of mometasone furoate spray after endoscopic operation of nasal polyps can improve the rehabilitation effect,promote the regression of nasal symptoms,and reduce the risk events and recurrence rate.
作者 刘全 Liu Quan(Otolaryngology Department of Zoucheng People’s Hospital,Jining,Shandong,273500,China)
机构地区 邹城市人民医院
出处 《中国医学文摘(耳鼻咽喉科学)》 2024年第3期10-12,16,共4页 Chinese Medical Digest(Otorhinolaryngology)
关键词 糠酸莫米松喷剂 鼻息肉 内镜 复发 Mometasone furoate spray Nasal polyps Endoscope Recrudescence
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