摘要
第五代头孢菌素类药物头孢洛林酯、头孢比罗酯钠抗菌谱较广,疗效佳,耐受性较好,安全性高,具有较高的临床价值,值得推广应用。本文通过对相关文献进行分析,归纳头孢洛林酯和头孢比罗酯钠的现有临床数据,就两种药物的作用机制、不良反应、耐药性研究及其在患者中的运用效果等方面进行综述。
The fth-generation ceftaroline fosamil and ceftobiprole medocaril sodium exhibit excellent safety,good tolerance,good efficacy,and a broad antibacterial range.So they have high clinical value.Additionally,they are worthy of promotion and application.This article reviews the mechanism of action,adverse reactions,drug resistance studies,and application effects of ceftaroline fosamil and ceftobiprole medocaril sodium by summarizing the available clinical data based on the analysis of pertinent literature.
作者
李诗媛
陈雨晞
贺彤
Li Shi-yuan;Chen Yu-xi;He Tong(Sichuan University,Chengdu 610207)
出处
《国外医药（抗生素分册）》
CAS
2024年第3期162-168,共7页
World Notes on Antibiotics
关键词
头孢洛林酯
头孢比罗酯钠
耐药性
临床研究
不良反应
ceftaroline fosamil
ceftobiprole medocaril sodium
drug resistance
clinical research
adverse reaction
