摘要
目的分析糖尿病患者中凝血四项检验的临床效果。方法选取2022年9月—2023年9月湖北省枣阳市中医医院收治的80例糖尿病患者作为研究组,将同一时期的40例健康人员作为对照组。研究组中40例空腹血糖≤8.8 mmol/L患者归为A组,40例空腹血糖>8.8 mmol/L患者归为B组,对比研究组与对照组凝血四项指标以及A组、B组、对照组3组凝血四项指标。结果对照组患者的凝血酶原时间(Prothrombin Time,PT)(12.89±0.47)s、活化部分凝血活酶时间(Activated Partial Thromboplastin Time,APTT)(34.76±3.28)s、凝血酶时间(Thrombin Time,TT)(17.66±1.43)s均高于研究组的(10.91±0.58)、(28.73±3.12)、(13.29±1.33)s,差异有统计学意义(P均<0.05)。对照组患者的纤维蛋白原(Fibrinogen,FIB)水平低于研究组,差异有统计学意义(P<0.05)。B组患者PT(12.12±0.35)s、APTT(31.49±3.17)s、TT(14.89±1.28)s,高于A组患者的(10.36±0.42)、(27.26±3.28)、(12.61±1.40)s,差异有统计学意义(P均<0.05);B组患者的FIB水平低于A组,差异有统计学意义(P<0.05)。且A、B两组PT、APTT、TT水平均低于对照组,FIB水平均高于对照组,差异有统计学意义(P均<0.05)。结论糖尿病患者进行凝血四项检验,能够区分其凝血功能状况,为疾病进展提供临床依据,对疾病的诊断、治疗和预后评估具有重要意义。
Objective To analyze the clinical effect of four coagulation tests in diabetic patients.Methods A total of 80 diabetic patients admitted to Zaoyang Hospital of Traditional Chinese Medicine in Hubei Province from September 2022 to September 2023 were selected as the study group,and 40 healthy persons in the same period were selected as the control group.In the study group,40 patients with fasting blood glucose≤8.8 mmol/L were assigned to group A,and 40 patients with fasting blood glucose>8.8 mmol/L were assigned to group B.The four coagulation indexes of the study group and the control group were compared.Four coagulation indexes of group A,group B and control group were compared.Results The prothrombin time(PT)(12.89±0.47)s,activated partial thromboplastin time(APTT)(34.76±3.28)s,thrombin time(TT)(17.66±1.43)s of the control group were higher than those of the study group[(10.91±0.58)s,(28.73±3.12)s,(13.29±1.33)s],and the differences were statistically significant(all P<0.05).The level of fibrinogen(FIB)in the control group was lower than that in the study group,and the difference was sta-tistically significant(P<0.05).PT(12.12±0.35)s,APTT(31.49±3.17)s,TT(14.89±1.28)s in group B were higher than those in group A[(10.36±0.42)s,(27.26±3.28)s,(12.61±1.40)s],the differences were statistically significant(all P<0.05).The level of FIB in group B was lower than that in group A,and the difference was statistically signifi-cant(P<0.05).The levels of PT,APTT and TT in group A and group B were lower than those in the control group,and the level of FIB was higher than that in the control group,and the differences were statistically significant(all P<0.05).Conclusion Four coagulation tests in diabetic patients can distinguish their coagulation function,provide clini-cal evidence for disease progression,and have great significance for the diagnosis,treatment and prognosis evaluation of the disease.
作者
赵海举
邹言章
ZHAO Haiju;ZOU Yanzhang(Zaoyang Hospital of Traditional Chinese Medicine,Zaoyang,Hubei Province,441200 China)
出处
《糖尿病新世界》
2024年第7期43-46,共4页
Diabetes New World Magazine
关键词
糖尿病
检验
凝血四项
临床效果
Diabetes mellitus
Test
Four coagulation items
Clinical effect
