摘要
目的:分析经皮冠状动脉介入治疗老年急性非ST段抬高型心肌梗死(NSTEMI)的应用效果。方法:回顾性选取2021年8月至2023年6月商丘市第一人民医院收治的老年急性NSTEMI患者88例,根据治疗方法的不同将予以保守治疗的40例患者作为对照组,将在对照组基础上应用经皮冠状动脉介入治疗的48例患者作为观察组。比较两组患者临床疗效、心功能指标、心力衰竭指标、肝肾功能指标、心血管不良事件发生情况。结果:观察组患者临床总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组患者左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)以及血清B型钠尿肽(BNP)水平低于对照组,左心室射血分数(LVEF)高于对照组,差异均具有统计学意义(P<0.05)。治疗后,两组患者血清丙氨酸转氨酶(ALT)、血肌酐(Scr)水平比较,差异无统计学意义(P>0.05)。观察组患者心血管不良事件总发生率低于对照组,差异具有统计学意义(P<0.05)。结论:经皮冠状动脉介入治疗老年急性NSTEMI患者,可增强临床效果,改善心功能,降低BNP水平,减少心血管不良事件发生。
Objective To analyze the effect of percutaneous coronary intervention in the treatment of elderly acute non-ST segment elevation myocardial infarction(NSTEMI).Methods A total of 88 elderly patients with acute NSTEMI admitted to the First People's Hospital of Shangqiu from August 2021 to June 2023 were retrospectively selected.According to different treatment methods,40 patients receiving conservative treatment were selected as a control group,and 48 patients receiving percutaneous coronary intervention on the basis of the control group were selected as an observation group.The clinical efficacy,cardiac function indexes,heart failure indexes,liveRand kidney function indexes,and cardiovasculaRadverse events were compared and observed between the two groups.Results The total clinical effective rate of the observation group was higherthan that of the control group,and the difference was statistically significant(P<0.05).Aftertreatment,the levels of left ventricularend diastolic diameter(LVEDD),left ventriculaRend systolic diameteR(LVESD)and B-type natriuretic peptide(BNP)in the observation group were lowerthan those in the control group,and left ventriculaRejection fractions(LVEF)was higherthan that in the control group,with statistical significances(P<0.05).Aftertreatment,there was no significant difference in the levels of serum alanine aminotransferase(ALT)and serum creatinine(Scr)between the two groups(P>0.05).The total incidence of cardiovasculaRadverse events in the observation group was lowerthan that in the control group,and the difference was statistically significant(P<0.05).Conclusion Percutaneous coronary intervention in elderly patients with acute NSTEMI can enhance clinical outcomes,improve cardiac function,reduce BNP levels,and reduce the occurrence of adverse cardiovasculaRevents.
作者
王明岗
朱永军
王勇
WANG Minggang;ZHU Yongjun;WANG Yong(The First People's Hospital of Shangqiu,Henan Shangqiu 476000)
出处
《深圳中西医结合杂志》
2024年第8期85-88,共4页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
急性非ST段抬高型心肌梗死
经皮冠状动脉介入
老年人
Non-ST segment elevation myocardial infarction
Percutaneous coronary intervention
The elderly
