摘要
目的:观察比较超声引导下5%葡萄糖和糖皮质激素注射治疗腰脊神经后支卡压综合征病人的疗效。方法:选择2023年1月至2023年6月徐州医科大学附属医院疼痛科86例腰脊神经后支卡压综合征病人,按随机数字表法分为5%葡萄糖(5%dextrose water,D5W)组(D5W组)和激素组(对照组)。D5W组采用超声下双侧脊神经后支注射30 ml 5%葡萄糖,对照组同样方法注射30 ml复方倍他米松稀释液。观察治疗前和治疗后1、2、4、12周的疼痛数字分级评分法(numerical rating scale,NRS)评分、Oswestry功能障碍指数(Oswestry disability index,ODI)、镇痛药物使用人数及不良反应;记录治疗前、治疗后第2天和第3天空腹末梢血糖变化。结果:与治疗前相比,两组治疗后1、2、4、12周NRS评分及ODI评分均降低;与对照组相比,D5W组治疗后12周的NRS评分及ODI评分也有所下降,D5W组对住院病人治疗后第2天和第3天空腹末梢血糖影响较小。治疗后2周,D5W组使用镇痛药物人数高于对照组。结论:超声引导下5%葡萄糖注射可缓解腰脊神经后支卡压综合征病人的疼痛,改善腰背功能,是治疗此类病人一种安全有效的方法。
Objective:To observe and compare the effectiveness of ultrasound-guided 5%dextrose water and corticosteroid injections in the treatment of patients with lumbar spinal nerve posterior branch syndrome.Methods:Eighty-six patients with lumbar spinal nerve posterior branch syndrome in the Pain Department of the Affiliated Hospital of Xuzhou Medical University from January 2023 to June 2023 were selected.They were randomly divided into two groups:the 5%dextrose water group(D5W group)and the corticosteroid group(Control group).Patients in D5W group were injected via ultrasound-guided with 30 ml of 5%dextrose water in the posterior branch of spinal nerves on both sides,the Control group was injected via ultrasound-guided with 30 ml of corticosteroid.Numerical rating scale(NRS),Oswestry disability index(ODI),the number of cases of analgesic use,and the occurrence of adverse reactions were observed before and 1,2,4,and 12 weeks after treatment.The fasting terminal blood glucose levels in hospitalized patients were recorded before treatment and on days 2 and 3 after treatment.Results:NRS and ODI scores were decreased significantly in both groups at 1,2,4,and 12 weeks after treatment compared to baseline.NRS as well as ODI scores were also reduced in the D5W group at 12 weeks after treatment compared to the Control group.During hospitalization,the D5W group had a smaller effect on the fasting terminal blood glucose on days 2 and 3 after treatment compared with the Control group.
作者
黄钰婷
张学广
陈立平
殷琴
袁燕
申文
HUANG Yu-ting;ZHANG Xue-guang;CHEN Li-ping;YIN Qin;YUAN Yan;SHEN Wen(Department of Pain Management,Affiliated Hospital of Xuzhou Medical University,Xuzhou 221006,China;Jiangsu Province Key Laboratory of Anesthesiology,Xuzhou Medical University,Xuzhou 221000,China;Department of Pain Management,West China Hospital,Sichuan University,Chengdu 610041,China)
出处
《中国疼痛医学杂志》
CAS
CSCD
北大核心
2024年第6期439-445,共7页
Chinese Journal of Pain Medicine
基金
国家自然科学基金(KC22235)。
关键词
超声引导
5%葡萄糖
腰脊神经后支卡压综合征
ultrasound-guided
5%dextrose water
lumbar spinal nerve posterior branch syndrome
