摘要
目的探讨慢性心力衰竭(心衰)患者的临床特征及心血管不良事件危险因素。方法选择2021年4月至2022年12月于太和县人民医院收治的135例慢性心衰患者进行研究,根据随访情况分为发生心血管不良事件组(n=41)和未发生心血管不良事件组(n=94)。收集患者临床资料,分析慢性心衰患者的临床特点,采用多因素Logistic回归模型分析慢性心衰发生心血管不良事件的危险因素。结果患者男女比率为61:74,NYHA心功能分级Ⅱ级32例,Ⅲ级71例,Ⅳ级32例。其中引起慢性心衰的病因主要为冠心病(45.93%,62/135)、高血压性心脏病(33.33%,45/135)、扩张型心肌病(12.59%,17/135),风湿性心脏病(2.22%,3/135)、肺源性心脏病(1.48%,2/135)、先天性心脏病(1.48%,2/135)及其他(2.96%,4/135)。随访发现,患者共发生心血管不良事件41例;单因素分析结果显示,两组患者在性别、体质指数(BMI)、高血压、心率、饮酒、心房颤动(房颤)、收缩压、舒张压、空腹血糖、糖化血红蛋白及合并疾病方面比较,差异均无统计学意义(P>0.05);而两组年龄、糖尿病、血脂异常、住院时间、吸烟等差异均有统计学意义(P<0.05)。多因素非条件Logistic回归结果显示,年龄、糖尿病、血脂异常、住院时间、吸烟均是慢性心衰患者发生心血管不良事件的独立危险因素(P<0.05)。结论慢性心衰患者的临床表现形式多样,应根据危险因素及时干预,以延缓疾病进展。
Objective To discuss the clinical features and risk factors of cardiovascular adverse events(CVAE)in patients with chronic heart failure(CHF).Methods CHF patients(n=135)were chosen from People’s Hospital of Taihe County from Apr.2021 to Dec.2022.All patients were divided,according to follow-up results,into CVAE group(n=41)and non-CVAE group(n=94).The clinical materials were collected and clinical features were analyzed in CHF patients.The risk factors of CVAE were analyzed by using multi-factor Logistic regression model.Results The radio of male to female was 61:74.There were 32 cases of gradeⅡof NYHA,71 cases of gradeⅢof NYHA and 32 cases of gradeⅣof NYHA.The causes of CHF were mainly coronary heart disease(45.93%,62/135),hypertension heart disease(33.33%,45/135),dilated cardiomyopathy(12.59%,17/135),rheumatic heart disease(2.22%,3/135),chronic pulmonary heart disease(1.48%,2/135),congenital heart disease(1.48%,2/135)and other CVAE(2.96%,4/135).There were totally 41 cases of CVAE in all patients during follow-up period.The results of single-factor analysis showed that the differences in gender,body mass index(BMI),hypertension,heart rate,drinking,atrial fibrillation,systolic blood pressure,diastolic blood pressure,fasting plasma glucose,glycated hemoglobin and complicated diseases had no statistical significance(P>0.05),while the differences in age,diabetes,dyslipidemia,length of hospital stay and smoking had statistical significance between 2 groups(P<0.05).The results of multi-factor non-conditional Logistic regression analysis showed that age,diabetes,dyslipidemia,length of hospital stay and smoking were independent risk factors for CVAE in CHF patients(P<0.05).Conclusion The clinical manifestations are various in forms in CHF patients,so the risk factors should be intervened in time to delay disease development.
作者
贾婉茹
项欣
王璐
尚文涛
薄晓红
Jia Wanru;Xiang Xin;Wang Lu;Shang Wentao;Bo Xiaohong(People's Hospital of Taihe County(Taihe Hospital affiliated to Wannan Medical College),Taihe 236600,China;不详)
出处
《中国循证心血管医学杂志》
2024年第3期304-306,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
基金
安徽省卫生健康科研项目(AHWJ2022c008)。
关键词
慢性心力衰竭
心血管不良事件
危险因素
Chronic heart failure
Cardiovascular adverse events
Risk factors
