摘要
目的:观察高强度聚焦超声消融术(HIFUA)联合桂枝茯苓丸治疗子宫肌瘤的临床疗效。方法:选取2020年1月—8月在江西省妇幼保健院住院治疗、年龄大于18岁、术前中医辨证属血瘀型的未绝经子宫肌瘤患者90例,随机分为观察组和对照组,各45例。观察组先行HIFUA治疗,术后口服桂枝茯苓丸3个月,对照组单纯采用HIFUA治疗。2组患者手术后1个月、3个月复查妇科B超,比较2组患者症状及生活质量改善情况。结果:(1)2组术后1个月、3个月子宫肌瘤缩小率比较,观察组均优于对照组,差异均有统计学意义(P<0.05);(2)2组术后1个月、3个月子宫肌瘤症状评分比较,观察组下降程度均优于对照组,健康相关生活质量问卷评分比较,观察组提高程度优于对照组,差异均有统计学意义(P<0.05)。结论:与单用HIFUA相比,HIFUA联合桂枝茯苓丸治疗子宫肌瘤的临床疗效更显著,肌瘤体积缩小率更大,症状及生活质量改善更明显,值得临床推广。
Objective:To observe the clinical efficacy of high intensity focused ultrasound ablation(HIFUA)combined with Guizhi Fuling pill in the treatment of uterine leiomyoma.Methods:From January 2020 to August 2020,90 cases of non-menopausal uterine leiomyoma,who were over 18 years old and belonged to blood stasis syndrome,were selected,they were randomly divided into observation group(n=45)and control group(n=45).The observation group was treated with HIFUA first,and Guizhi Fuling pill was orally taken for 3 months after operation,while the control group was treated with HIFUA only.The improvement of symptoms and quality of life were compared between the two groups at 1 month and 3 months after operation.Results:(1)Compared with the control group,the shrinkage rate of uterine leiomyoma in the observation group was better than that in the control group at 1 month and 3 months after operation(P<0.05);(2)comparing the symptom scores of hysteromyoma at 1 month and 3 months after operation,the decrease degree of the observation group was better than that of the control group,and the improvement degree of the health-related quality of life questionnaire was better than that of the control group,the difference was significant(P<0.05).Conclusion:Compared with single use of HIFUA,HIFUA combined with Guizhi Fuling pill is more effective in the treatment of uterine leiomyoma,the reduction rate of uterine leiomyoma volume is larger,the improvement of symptoms and quality of life is more obvious,and it is worthy of clinical promotion.
作者
廖红
梁影
陈智园
叶甜甜
刘欣
周佳穗
李芳
LIAO Hong;LIANG Ying;CHEN Zhiyuan;YE Tiantian;LIU Xin;ZHOU Jiasui;LI Fang(Jiangxi Provincial Maternal and Child Health Hospital,Nanchang 330006,China)
出处
《江西中医药大学学报》
2024年第3期50-53,共4页
Journal of Jiangxi University of Chinese Medicine
关键词
高强度聚焦超声消融术
桂枝茯苓丸
子宫肌瘤
血瘀证
High Intensity Focused Ultrasound Ablation
Guizhi Fuling Pill
Hysteromyoma
Blood Stasis Syndrome
