摘要
目的:探究桃红四物汤合防己黄芪汤结合空气压力波治疗仪(IPC)对预防胸腰椎骨折术后下肢深静脉血栓(DVT)的疗效。方法:选取2019年5月~2022年5月行胸腰椎骨折修复术的患者92例,随机分为中药组和常规组,各46例,患者术后均给予基础治疗,常规组加用IPC治疗,中药组在常规组基础上加予桃红四物汤合防己黄芪汤,两组均治疗2周。比较两组DVT发生率、下肢血流动力学指标、凝血指标、下肢视觉模拟评分(VAS)、肢体周径,记录治疗期间不良反应。结果:中药组DVT发生率为13.04%,低于常规组的30.43%(P<0.05);治疗后,两组股总静脉、腘静脉流速、血浆凝血酶原时间(PT)、部分活化凝血活酶时间(APTT)均升高(P<0.05),且相较于常规组,中药组上述指标更高(P<0.05);治疗后,两组D-二聚体(DD)、VAS评分、肢体周径均下降(P<0.05),且相较于常规组,中药组上述指标更低;两组治疗期间不良反应无明显差异(P>0.05)。结论:桃红四物汤合防己黄芪汤结合IPC能明显降低胸腰椎骨折术后DVT的发生,加速下肢血流,改善其凝血功能,降低下肢肿胀、疼痛程度,值得临床应用。
Objective To explore the efficacy of Taohong Siwu decoction with Fangji Huangqi decoction combined with intermittent pneumatic compression(IPC)on the prevention of lower limb deep venous thrombosis(DVT)after thoracolumbar fracture surgery.Methods 92patients who underwent thoracolumbar fracture repair were enrolled between May 2019and May 2022and randomly divided into TCM group(n=46)and conventional group(n=46).Patients were given basic treatment after surgery,and the conventional group was added with IPC while the TCM group was treated with Taohong Siwu decoction with Fangji Huangqi decoction on the basis of the conventional group,and both groups were treated for 2weeks.Comparisons were performed on the two groups from the aspects of incidence rate of DVT,lower limb hemodynamic indexes,coagulation indexes,lower limb visual analogue scale score(VAS)and limb circumference,and the adverse reactions were recorded during treatment.Results The incidence rate of DVT in TCM group was 13.04%,which was lower than 30.43%in conventional group(P<0.05).After treatment,the flow velocities of the common femoral vein and popliteal vein and prothrombin time(PT)and activated partial thromboplastin time(APTT)were increased in both groups(P<0.05),and the above indexes in TCM group were higher compared with those in conventional group(P<0.05).The D-dimer(DD),VAS score and limb circumference in both groups were declined after treat-ment(P<0.05),and the above indexes in TCM group were lower than those in conventional group(P<0.05).There were no significant differences in adverse reactions between both groups during treatment(P>0.05).Conclusion Taohong Siwu decoction with Fangji Huangqi decoction combined with IPC can significantly reduce the occurrence of DVT after thoracolumbar fracture surgery,accelerate the lower limb blood flow,improve the coagulation function,and reduce the lower limb swelling degree and pain degree.
作者
张艳
陈小龙
刘静
张秀珍
ZHANG Yan;CHEN Xiaolong;LIU Jing(Taihe Hospital of traditional Chinese medicine,Anhui University of Chinese medicine,Taihe Anhui 236600,China)
出处
《四川中医》
2024年第4期127-130,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
安徽省科技计划项目(编号:2204f0804012)。
关键词
桃红四物汤合防己黄芪汤
空气压力波治疗仪
胸腰椎骨折术后
DVT
下肢血流动力学指标
凝血功能
Taohong Siwu decoction with Fangji Huangqi decoction
Air pressure wave therapy apparatus
After thoracolumbar fracture surgery
DVT
Lower limb hemodynamic indexes
Coagulation function
