摘要
炎症性心肌病是指各种原因导致心肌炎症激活进而发展为心肌病的统称,其中心肌炎是导致心肌功能障碍最直接的原因。本文将论述免疫反应在炎症性心肌病(尤其是病毒性心肌炎)病情进展中的作用机制,主要从固有免疫、获得性免疫和自身免疫等方面进行讨论,并论述免疫抑制治疗在临床及临床前研究中对炎症性心肌病的作用、目前存在的问题及发展趋势。
Inflammatory cardiomyopathy is a general term for cardiomyopathy caused by activation of myocardium inflammation for various reasons,among which myocarditis is the most direct cause of myocardial dysfunction.This article mainly discusses the mechanism of immune response in the progression of inflammatory cardiomyopathy(especially viral myocarditis),and mainly covers with innate immunity,acquired immunity and autoimmunity etc.And it also discusses the effects,current existing problems and development trends of immunosuppressive therapy on inflammatory cardiomyopathy in clinical and preclinical studies.
作者
张玉
傅永旺
ZHANG Yu;FU Yong-wang(Department of Hyperbaric Oxygen,People's Hospital of Inner Mongolia Autonomous Region,Hohhot,Inner Mongolia,737399,China)
出处
《心血管康复医学杂志》
CAS
2024年第3期354-357,共4页
Chinese Journal of Cardiovascular Rehabilitation Medicine
基金
内蒙古自治区人民医院院内基金项目(2019YN07)。
关键词
心肌疾病
炎症
免疫
Cardiomyopathies
Inflammation
Immunity
