摘要
目的通过某三甲妇儿专科医院临床药师对新生儿科使用美罗培南的干预分析,为新生儿科临床药师参与临床药学工作提供参考,促进临床规范使用美罗培南。方法回顾性分析该院新生儿科临床药师未参与该科室临床查房前半年(2017年1—6月)所有使用美罗培南的病历123份(干预前组),参与该科室查房进行用药干预后(2020年1—6月)所有使用美罗培南病历70份(干预后组)。研究比较新生儿科临床药师干预前后,美罗培南在适应证、用法用量及配伍、病原学及疗效评估、联合用药等方面的情况。结果干预后组所有使用美罗培南的病历在适应证、用法用量、降阶梯时机,联合用药方面情况均较干预前组得到显著改善,差异均有统计学意义(P<0.05)。结论新生儿科临床药师深度参与临床工作进行用药干预,对碳青霉烯类抗菌药物的规范使用、持续改善起到较大推动作用。
Objective To provide reference for clinical pharmacists in neonatology to participate in clinical pharmacy and to promote the standardized clinical use of Meropenem through the analysis of the intervention of clinical pharmacists on the use of Meropenem in neonatology in a tertiary care women′s and children′s specialty hospital.Methods Retrospective analysis of 123 medical records of all Meropenem use in the neonatology department of the hospital in the six months(January-June 2017)before the clinical pharmacist did not participate in the clinical checkup of the department(pre-intervention group),and 70 medical records of all Meropenem use after the participation(January-June 2020)in the checkup of the department for medication intervention(post-intervention group).The study compared Meropenem before and after the clinical pharmacist intervention in the neonatal unit in terms of indications,dosage and dosing,pathogenetic and efficacy assessment,and co-administration of Meropenem.Results After the intervention,all the medical records of Meropenem in the post-intervention group were significantly improved in terms of indications,dosage,timing of step-downs,and combinations compared with those of the pre-intervention group,and the differences were statistically significant(P<0.05).Conclusion The deep involvement of clinical pharmacists in the neonatal department in clinical work for medication intervention plays a greater role in promoting the standardized use and continuous improvement of carbapenem antimicrobials.
作者
李云送
林万龙
黄志毅
LI Yunsong;LIN Wanlong;HUANG Zhiyi(Women and Children′s Hospital School of Medicine Xiamen University,Xiamen,Fujian 361003,China)
出处
《现代医药卫生》
2024年第11期1879-1883,共5页
Journal of Modern Medicine & Health
关键词
美罗培南
新生儿科
临床药师
用药干预
Meropenem
Neonatal Pediatrics
Clinical pharmacist
Medication intervention
