摘要
目的 基于名医传承平台分析《中华医典》中治疗腹胀满病的方剂用药规律。方法 检索《中华医典》收集治疗腹胀满病的方剂,利用名医传承平台对中药四气、五味、归经,核心药物、药物配伍,药-症关联,药物聚类等进行数据挖掘。结果 纳入201首方剂,共273味中药,常用中药四气以温、寒、平为主;五味以辛、苦、甘为主;归经以脾、胃、肺经为主。核心药物有甘草、陈皮等25味。常用中药配伍有黄连-黄芩等27个药对。对支持度≥0.05的中药进行聚类分析,共获得10个药物群。存在以枳实-木香-黄连治腹痛等药-症关联规律。结论《中华医典》中治疗腹胀满病的方剂用药以调脾胃为主,多采用理气、祛湿,配合消食、清热、活血、补气、养血等法,挖掘出的药对、药物群、药-症组合可供临床化裁使用。
Objective To analyze the prescription medication rules for the treatment of abdominal distension and fullness disease in Chinese Medical Classics based on the Inheritance Platform of Famous Doctors.Methods The Chinese Medical Classics was searched to collect the prescriptions for the treatment of abdominal distension,and the data mining was carried out on the four nature,five flavours,channel tropism of Chinese materia medica,core drug,drug compatibility,drugsyndrome association,drug clustering,etc.,using the Inheritance Platform of Famous Doctors.Results A total of 201prescriptions were included,with a total of 273 kinds of Chinese materia medica.The four nature of commonly used Chinese materia medica were mainly warm,cold,and plain.The five flavours of Chinese materia medica were mainly sweet,bitter,and sweet.Spleen,stomach,and lung channels were the main channels.There were 25 kinds of core drug,such as Glycyrrhizae Radix Et Rhizoma and Citri Reticulatae Pericarpium.There were 27 couplet medicines of commonly used Chinese materia medica,such as Coptidis Rhizoma-Scutellariae Radix.By cluster analysis,ten drug groups were obtained with support degree ≥0.05.There was a correlation law of the drug-symptoms of treating abdominal pain with Aurantii Fructus Immaturus-Aucklandiae Radix-Coptidis Rhizoma.Conclusion The prescriptions for the treatment of abdominal distension and fullness disease in the Chinese Medical Classics are mainly used to regulate the spleen and stomach,and mostly adopt the methods of regulating qi and dispelling dampness,combining with digestion,clearing heat,promoting blood circulation,invigorating qi,and nourishing blood,etc.The couplet medicines,drug groups,and drug-disease combinations excavated can be used in clinical treatment.
作者
王紫兮
王佳佳
王文娟
WANG Zixi;WANG Jiajia;WANG Wenjuan(College of Traditional Chinese Medicine,Capital Medical University,Beijing 100069,China)
出处
《中国医药导报》
CAS
2024年第12期6-10,15,共6页
China Medical Herald
基金
国家重点研发计划“中医药现代化研究”专项项目(2018YFC1704102)
国家自然科学基金青年科学基金资助项目(82104765)。
关键词
腹胀满病
方剂
用药规律
名医传承平台
Abdominal distension and fullness disease
Prescriptions
Medication rules
Inheritance Platform of Famous Doctors
