摘要
目的探究自拟黄芪败酱汤治疗妇科手术后发热患者的临床疗效。方法选取该院妇科住院部术后发热患者80例,采用随机数字表法分为治疗组40例和对照组40例,对照组给予亚胺培南抗感染、补液等常规治疗,治疗组在对照组基础上加以自拟黄芪败酱汤辨证治疗,比较两组治疗后临床有效率、中医症状积分、体温变化(第一次体温恢复正常时间、体温波动幅度、住院时间)、炎症反应[白细胞计数(WBC)、C反应蛋白(CRP)、降钙素原(PCT)、白细胞介素-6(IL-6)],记录两组患者治疗期间不良反应。结果治疗后,治疗组临床有效率为92.5%(37/40),明显高于对照组的72.5%(29/40),差异有统计学意义(P<0.05);治疗后,两组主症及次症中医症状积分均降低(P<0.05),且治疗组治疗后低于对照组(P<0.05);两组体温均较治疗前逐渐降低(P<0.05),且治疗组治疗第3~7天体温低于对照组,差异有统计学意义(P<0.05);治疗组首次体温恢复时间以及住院时间均较对照组短(P<0.05);治疗第3、5天,两组WBC、CRP、PCT、IL-6水平较治疗前逐渐降低,组内不同时间点比较差异有统计学意义(P<0.05),且治疗组治疗第3、5天时上述指标均低于对照组,差异有统计学意义(P<0.05);治疗期间,两组均未见明显不良反应。结论自拟黄芪败酱汤可提高妇科手术后发热患者的临床有效率,改善患者症状和炎症反应,临床应用价值较高。
Objective To explore the clinical efficacy of Self-made Huangqi Baijiang Decoction(自拟黄芪败酱汤)in the treatment of patients with fever after gynecological surgery.Methods Eighty patients with postoperative fever in gynecological inpatient department of the hospital were selected and divided into treatment group(40 cases)and control group(40 cases)by the random number table method.The control group was given imipenem anti-infection,fluid replacement and other conventional treatments,and the treatment group was additionally treated with Self-made Huangqi Baijiang Decoction on the basis of the control group.The clinical effective rate,TCM symptoms scores,body temperature changes(time of first body temperature returning to be normal,the range of body temperature fluctuation,hospital stay)and inflammatory response[white blood cell count(WBC),C-reactive protein(CRP),procalcitonin(PCT),interleukin-6(IL-6)]were compared between the two groups after treatment,and the adverse reactions of the two groups during treatment were recorded.Results After treatment,the clinical effective rate in the treatment group was 92.5%(37/40),which was significantly higher than 72.5%(29/40)in the control group(P<0.05).After treatment,the scores of primary and secondary TCM symptoms in the two groups were reduced(P<0.05),and the scores in the treatment group were lower than those in the control group(P<0.05).The body temperature of the two groups was declined gradually compared with that before treatment(P<0.05),and the body temperature in the treatment group was lower than that in the control group on the 3 rd day to 7 th day of treatment(P<0.05).The first body temperature recovery time and hospital stay in the treatment group were shorter compared with those in the control group(P<0.05).On the 3 rd day and 5 th day of treatment,the levels of WBC,CRP,PCT and IL-6 in the two groups were gradually decreased compared to those before treatment,and the differences were significant at different time points within the groups(P<0.05),and t
作者
姜林
杨改红
孔令超
JIANG Lin;YANG Gaihong;KONG Lingchao(Handan Mingren Hospital,Handan 056001,Hebei,China)
出处
《辽宁中医杂志》
CAS
北大核心
2024年第6期131-135,共5页
Liaoning Journal of Traditional Chinese Medicine
基金
河北省中医药管理局科研计划项目(2021477)。
关键词
自拟黄芪败酱汤
妇科术后发热
临床疗效
中医症状积分
体温变化
炎症反应
Self-made Huangqi Baijiang Decoction(自拟黄芪败酱汤)
fever after gynecological surgery
clinical efficacy
TCM symptoms scores
body temperature changes
inflammatory response
