摘要
目的:分析极/超低出生体重儿出生后1周内并发高血糖的影响因素。方法:回顾2016年8月—2023年8月在上饶市人民医院新生儿科出生的300例极/超低出生体重儿资料,根据出生后1周内是否并发高血糖(空腹血糖>7 mmol/L)分为正常组(n=220)和异常组(n=80),比较两组资料。结果:出生后1周内高血糖发生率26.67%(80/300),发生时间多在24 h内,平均高血糖持续时间(3.44±0.52)d,首发高血糖浓度平均(9.34±1.03)mmol/L;异常组体重<1500 g、5 min新生儿Apgar评分≤7分、胎龄<28周比例均高于正常组,差异均有统计学意义(P<0.05);异常组新生儿母亲年龄≥35岁、妊娠期糖尿病、妊娠期高血压疾病比例均高于正常组,差异均有统计学意义(P<0.05);异常组新生儿葡萄糖输注速度4~6 mg/(kg·min)、禁食时长≤1 d比例均低于正常组,机械通气、新生儿窒息比例均高于正常组,差异均有统计学意义(P<0.05);体重、胎龄、5 min新生儿Apgar评分、葡萄糖输注速度、新生儿窒息是极/超低出生体重儿出生后1周内并发高血糖的影响因素(P<0.05)。结论:极/超低出生体重儿出生后1周内高血糖发生率较高,体重、胎龄、5 min新生儿Apgar评分、葡萄糖输注速度、新生儿窒息是其影响因素,临床应针对上述指标针对性预防。
Objective:To analyze the influencing factors of hyperglycemia in very/extremely low birth weight infants within 1 week after birth.Method:The data of 300 very/extremely low birth weight infants born in Department of Neonatology of Shangrao People's Hospital from August 2016 to August 2023 were reviewed.According to the presence or absence of hyperglycemia(fasting blood glucose>7 mmol/L)within 1 week after birth,they were divided into normal group(n=220)and abnormal group(n=80),and the data of the two groups were compared.Result:The incidence rate of hyperglycemia was 26.67%(80/300)within 1 week after birth,and the occurrence time was mostly within 24 hours,average duration of hyperglycemia was(3.44±0.52)d and the average blood glucose concentration of first hyperglycemia was(9.34±1.03)mmol/L.The proportions of body weight<1,500 g,5 min neonatal Apgar score≤7 points and gestational age<28 weeks in abnormal group were higher compared to normal group,the differences were statistically significant(P<0.05).The proportions of maternal age≥35 years old,gestational diabetes mellitus and gestational hypertension in abnormal group were higher than those in normal group,with statistical differences(P<0.05).The proportions of neonatal glucose infusion speed of 4-6 mg/(kg·min)and fasting duration≤1 d in abnormal group were lower than those in normal group,and the proportions of mechanical ventilation and neonatal asphyxia were higher compared with those in normal group,with statistically significant differences(P<0.05).Body weight,gestational age,5 min neonatal Apgar score,glucose infusion speed and neonatal asphyxia were the influencing factors of hyperglycemia in very/extremely low birth weight infants within 1 week after birth(P<0.05).Conclusion:The incidence rate of hyperglycemia is high in very/extremely low birth weight infants within 1 week after birth,and body weight,gestational age,5 min neonatal Apgar score,glucose infusion speed and neonatal asphyxia are the influencing factors,and it is necessary to perfo
作者
李欢
尹冬琴
徐文慧
温晓芳
LI Huan;YIN Dongqin;XU Wenhui;WEN Xiaofang(Department of Neonatology,Shangrao People's Hospital,Shangrao 334000,China;不详)
出处
《中国医学创新》
CAS
2024年第13期125-129,共5页
Medical Innovation of China
关键词
极/超低出生体重儿
新生儿高血糖症
影响因素
Very/extremely low birth weight infants
Neonatal hyperglycemia
Influencing factors
