摘要
目的建立肺通气检查禁忌人群第1秒用力呼吸容积(FEV1)预计式,以推测此人群FEV1预计值。方法本实验分为回顾性研究及前瞻性研究。回顾性收集病例资料1,273例作为建模实验组;前瞻性收集验证组375例。收集基本资料、肺功能测定FEV1值及强迫振荡技术(FOT)测定呼吸阻力R5值。采用Pearson相关分析探究实验组各因素与FEV1相关性。多元线性回归分析,建立预计方程。配对t检验验证组FEV1真实值和预计值差异。结果FEV1与体质量无模型相关关系,与身高呈正相关关系,年龄呈负相关关系,R5呈负相关关系(P<0.05)。建模与验证:纳入身高、年龄和R5,实际值与预计值在验证样本中无统计学差异(P>0.05),且验证样本两值相关性好。结论本研究人群中FEV1真实值与预计值无统计学差异,模型有较好的准确性,可应用于临床诊疗。
Objective To establish the forced expiratory volume in one second(FEV1)prediction formula for the population who are contraindicated for pulmonary ventilation examination,so as to estimate the predicted value of FEV1 in this population.Methods 1273 patients in the experimental group were collected retrospectively.375 patients in the verification group were collected prospectively.Basic data were collected,FEV1 value of pulmonary function was measured and R5 value of respiratory resistance was measured by forced oscillation technique(FOT).Pearson correlation analysis was used to explore the correlation between physiological factors and FEV1 in the experimental group.Multiple linear regression analysis and prediction equation were established.The paired T-test examined the difference between the true and predicted FEV1 values of the verification group.Results FEV1 had no model correlation with body weight,positive correlation with height,negative correlation with age,and negative correlation with R5.Modeling and verification:height,age and R5 are included.There was no statistical difference between the actual value and the predicted value in the verification sample,and the correlation between the two values of the verification sample was good.Conclusion There is no statistical difference between the real value of FEV1 and the predicted value in the study population,indicating that the model has good accuracy and is suitable for clinical use.
出处
《浙江临床医学》
2024年第5期680-682,共3页
Zhejiang Clinical Medical Journal
