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VSD联合异烟肼冲洗在颈部淋巴结结核功能性清扫术后中的应用效果

Application effect of VSD combined with isoniazid irrigation in functional cervical tuberculous lymphadenopathy clearance surgery
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摘要 目的探讨颈部淋巴结结核(CTL)功能性清扫术后应用负压封闭引流(VSD)联合异烟肼冲洗治疗的临床效果。方法回顾性分析2021年3月—2023年3月本院CTL行功能性颈淋巴清扫术患者的临床资料,根据术后引流方式不同分为常规引流组(异烟肼冲洗+常规纱条填塞引流换药)和VSD组(异烟肼冲洗+VSD),采用倾向性评分法(卡钳值设置0.02)排除基线资料混杂因素影响,最终1∶1比例匹配获得每组各49例基线资料可比患者。比较2组围术期指标(第1周残腔缩小百分比、术后引流时间、创面愈合时间、术后换药次数),术后12 h、24 h、48 h视觉疼痛模拟量表(VAS)评分、切口I期愈合率及术后并发症发生情况。结果VSD组患者第1周残腔缩小百分比高于常规引流组,差异有统计学意义(P<0.05);VSD组患者术后引流时间、创面愈合时间短于常规引流组,术后换药次数少于常规引流组,差异均有统计学意义(P<0.05)。2组患者术后24 h、术后48 h时VAS评分均低于术后12 h,且VSD组术后24 h、术后48 h时VAS评分均低于常规引流组,差异均有统计学意义(P<0.05)。VSD组患者切口I期愈合率高于常规引流组,差异有统计学意义(P<0.05)。2组患者术后并发症发生率比较,差异无统计学意义(P>0.05)。结论CTL患者在功能性清扫术后采用VSD联合异烟肼冲洗治疗,有利于加速残腔愈合,缩短引流时间及减少换药次数,减轻术后创面疼痛感,提高I期愈合率,降低术后并发症发生风险。 Objective To explore the clinical effect of vacuum sealing drainage(VSD)combined with isoniazid irrigation in the treatment of cervical tuberculous lymphadenopathy(CTL)after functional clearance surgery.Methods A retrospective analysis was conducted on the clinical data of patients who underwent functional clearance surgery for cervical tuberculous lymphadenopathy in our hospital from March 2021 to March 2023.According to different postoperative drainage methods,they were allocated to the conventional drainage group(isoniazid irrigation+conventional gauze packing drainage and dressing change)and the VSD group(isoniazid irrigation+VSD).The propensity score matching method(caliper value set at 0.02)was used to exclude the confounding factors of baseline data,and finally,comparable patients with a 1:1 ratio of 49 patients in each group were obtained.The perioperative indicators(percentage of residual cavity reduction in the first week,postoperative drainage time,wound healing time,and the number of dressing changes),visual analog scale(VAS)scores at 12 hours,24 hours,and 48 hours after surgery,incision healing rate in stage I,and postoperative complications were compared between the two groups.Results The percentage of residual cavity reduction in the first week was higher in the VSD group than in the conventional drainage group,with a statistically significant difference(P<0.05).The postoperative drainage time and wound healing time were shorter,and the number of dressing changes was fewer in the VSD group than in the conventional drainage group,with statistically significant differences(P<0.05).The VAS scores at 24 hours and 48 hours after surgery in both groups were lower than those at 12 hours after surgery,and the VAS scores at 24 hours and 48 hours in the VSD group were lower than those in the conventional drainage group,with statistically significant differences(P<0.05).The incision healing rate in stage I was significantly higher in the VSD group than in the conventional drainage group(P<0.05).No statistical
作者 邓贵芳 Deng Guifang(Public Health Clinical Center of Chengdu,Chengdu 610066,China)
出处 《保健医学研究与实践》 2023年第S02期99-101,共3页 Health Medicine Research and Practice
关键词 颈部淋巴结结核 功能性清扫术 负压封闭引流 异烟肼 临床效果 Cervical tuberculous lymphadenopathy Functional clearance surgery Vacuum sealing drainage Isoniazid Clinical effect
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