摘要
背景过敏性疾病的患病率在全球人群中急剧增长,已经影响着10%~40%的世界人口。该类疾病常在儿童期始发,但我国尚缺乏10年内儿童过敏性疾病发病率趋势分析数据,本研究拟通过对单中心电子病历数据进行挖掘,从而为国内过敏性疾病预防和管理工作的开展提供流行病学支持。目的分析2014—2021年首都医科大学附属北京儿童医院0~18岁儿童过敏性疾病门诊就诊年度构成比及变化趋势。方法回顾性分析首都医科大学附属北京儿童医院2014—2021年医院信息系统门诊电子病历数据,对过敏性疾病就诊年度构成比及变化趋势进行分析。计算不同性别、年龄过敏性疾病包括湿疹、荨麻疹、过敏性鼻炎、支气管哮喘、过敏性咳嗽、过敏性结膜炎、食物过敏、药物过敏、花粉症、严重过敏反应等疾病的就诊年度构成比。进一步分析年度构成比排名稳定在前10位的过敏性疾病构成比变化趋势。结果2014—2021年门诊过敏性疾病就诊儿童累计1231890例次,去除缺失数据后共纳入1231863例次,其中男童727082例次(59.0%),女童504781例次(41.0%);过敏性疾病就诊患儿年龄以3岁以下为主(46.9%)。删除过敏性紫癜、支气管炎、呼吸道感染等非免疫球蛋白E介导的过敏性疾病,纳入疾病谱分析病例1208265例次。2016—2021年首都医科大学附属北京儿童医院儿童过敏性疾病门诊就诊例次在全院门诊就诊例次中的占比呈上升趋势。2014—2017年儿童过敏性疾病门诊就诊构成比前5位分别是湿疹、荨麻疹、过敏性鼻炎、支气管哮喘、过敏性咳嗽;2018—2021年儿童过敏性疾病门诊就诊构成比前5位分别是过敏性鼻炎、湿疹、荨麻疹、过敏性结膜炎、支气管哮喘。年度构成比变化趋势分析显示,2014—2021年,过敏性鼻炎、过敏性结膜炎及食物过敏占全部过敏性疾病的构成比呈逐年上升趋势,构成比峰值分别达45.4%�
Background The prevalence of allergic diseases is rapidly increasing among the global population,affecting 10%-40%of people worldwide.Allergic diseases often begin in childhood.So far,data for analyzing the trends in the incidence of pediatric allergic diseases in China over the past decade are scant.This study aims to provide an epidemiological support for the prevention and management of pediatric allergic diseases in China by mining electronic medical record data from a single-center institution.Objective To analyze the annual proportion and trend of outpatient visits for allergic diseases among children aged 0-18 years in the Beijing Children's Hospital,Capital Medical University from 2014 to 2021.Methods A retrospective analysis of outpatient electronic medical records from the hospital information system of Beijing Children's Hospital,Capital Medical University from 2014 to 2021 was conducted to examine the annual proportional composition and changes in the trend changes of allergic diseases.The gender-and age-based proportions of different allergic diseases including eczema,urticaria,allergic rhinitis,bronchial asthma,allergic cough,allergic conjunctivitis,food allergies,drug allergies,pollen allergy,and anaphylaxis were calculated.The trend of changes in the proportion of allergic diseases with stable annual composition ranking in the top 10 was further analyzed.Results From 2014 to 2021,there were a total of 1231890 outpatient visits for pediatric allergic diseases in our center.After excluding missing data,a total of 1231863 eligible cases were included,involving 727082(59.0%)boys and 504781(41.0%)girls.The majority of children visited for allergic diseases were under the age of 3 years(46.9%).Non-IgE mediated allergic diseases,such as henoch-schoenlein purpura,bronchitis,and respiratory tract infections were excluded,and the remaining 1208265 cases included in the disease spectrum analysis.From 2016 to 2021,the proportion of outpatient visits for pediatric allergic diseases in Beijing Children's Hospit
作者
侯晓玲
皇惠杰
姜楠楠
李昂
孔勤
魏勉
向莉
HOU Xiaoling;HUANG Huijie;JIANG Nannan;LI Ang;KONG Qin;WEI Mian;XIANG Li(Department of Allergy,Beijing Children's Hospital,Capital Medical University/National Center for Children's Health/Key Laboratory of Major Diseases in Children,Ministry of Education/National Clinical Research Center for Respiratory Diseases,Beijing 100045,China;Department of Information Center,Beijing Children's Hospital,Capital Medical University/National Center for Children's Health/Key Laboratory of Major Diseases in Children,Ministry of Education/National Clinical Research Center for Respiratory Diseases,Beijing 100045,China)
出处
《中国全科医学》
CAS
北大核心
2024年第27期3395-3400,共6页
Chinese General Practice
基金
国家呼吸系统疾病临床医学研究中心呼吸专项(HXZX-20210204)
北京儿童医院管理课题项目(YGLZ2022001)。
关键词
过敏反应
过敏性疾病
儿童
门诊医疗
构成比
趋势分析
北京
Anaphylaxis
Allergic diseases
Child
Ambulatory care
Proportion
Trend analysis
Beijing
