摘要
目的分析在治疗糖尿病视网膜病变和静脉阻塞性黄斑水肿时,使用雷珠单抗结合眼底激光的作用。方法选取2021年7月—2023年7月巨野县人民医院收治的因糖尿病视网膜病变和视网膜静脉阻塞引发黄斑水肿症的82例患者为研究对象,按照随机数表法将患者分成参照组(n=41)及联合组(n=41)。参照组仅实施眼底激光疗法;联合组则在眼底激光疗法基础上联合雷珠单抗治疗。对比两组患者的临床指标。结果联合组的临床症状改善时间短于参照组,差异有统计学意义(P<0.05)。干预后联合组的黄斑中心凹厚度比参照组低,最佳矫正视力比参照组高,差异有统计学意义(P均<0.05)。联合组的并发症的发生率(4.88%)比参照组(9.76%)低,但差异无统计学意义(χ^(2)=0.719,P>0.05)。结论将雷珠单抗和眼底激光用于糖尿病视网膜病变及静脉阻塞性黄斑水肿的治疗,可显著提高视力,且能降低黄斑厚度,改善临床症状,具有较好的临床应用价值。
Objective Analyze the effect of using Lucentis combined with fundus laser in the treatment of diabetic retinopathy and macular edema due to venous obstruction.Methods A total of 82 patients with macular edema caused by diabetic retinopathy and retinal vein occlusion admitted to Juye County People's Hospital from July 2021 to July 2023 were selected as study objects,and the patients were divided into the reference group(n=41)and the combined group(n=41)according to the method of random number table.In the reference group,only fundus laser therapy was implemented,while in the combination group,Lucentis was combined with fundus laser therapy.The clinical indicators of the two groups were compared.Results The clinical symptoms of the combination group all improved in a shorter time than the reference group,and the difference was statistically significant(P<0.05).Central foveat thichness was lower and best cooected visual acuity was higher in the combination group than those in the reference group after the intervention,and the differences were statistically significant(both P<0.05).The total complication rate(4.88%)was lower in the combination group than in the reference group(9.76%),but the difference was not statistically significant(χ^(2)=0.719,P>0.05).Conclusion The use of Lucentis and fundus laser for the treatment of diabetic retinopathy and venous-obstructive macular edema can significantly improve visual acuity,and it can reduce the macular thickness and improve the clinical symptoms,which is of good clinical application value.
作者
贾黎明
王亚军
JIA Liming;WANG Yajun(Department of Ophthalmology,Juye County People's Hospital,Heze,Shandong Province,274900 China)
出处
《系统医学》
2024年第7期83-86,共4页
Systems Medicine
