摘要
目的探讨米索前列醇在产科临床应用中对产后出血的治疗效果。方法选取本院产科诊疗的100例产后出血患者为研究对象,依据病案号奇偶数将其分为两组,各50例。对照组予以缩宫素治疗,研究组予以米索前列醇治疗,比较两组的凝血功能、血清学指标及出血量。结果治疗后,研究组凝血酶原时间、活化部分凝血活酶时间、D-二聚体、纤维蛋白原、一氧化氮、一氧化氮合酶低于对照组(P<0.05);治疗后,研究组治疗后0.5h、治疗后0.6~2h、治疗后3~24h出血量均少于对照组(P<0.05)。结论米索前列醇治疗产后出血,能减少患者出血量,改善凝血功能,并降低其血清学指标,应用价值显著。
Objective To explore the therapeutic effect of misoprostol on postpartum hemorrhage in obstetric clinical application.Methods 1oo postpartum hemorrhage patients diagnosed and treated in the obstetrics department of our hospital were selected as the research subjects.They were divided into two groups based on odd and even medical record numbers,with 50 cases in each group.The control group was treated with oxytocin,while the study group was treated with misoprostol.The coagulation function,serological indicators,and bleeding volume of the two groups were compared.Results After treatment,the prothrombin time,activated partial thromboplastin time,D-dimer,fibrinogen,nitric oxide,and nitric oxide synthase in the study group were lower than those in the control group(P<o.05);After treatment,the study group had less bleeding than the control group at 0.5 hours,0.6~2 hours,and 3~24 hours after treatment(P<0.05).Conclusion Misoprostol treatment for postpartum hemorrhage can reduce the amount of bleeding in patients,improve coagulation function,and lower its serological indicators,with significant application value.
作者
戴春丽
Dai Chunli(Department of Obstetrics,Pingnan Maternal and Child Health Hospital,Guigang 537300,China)
出处
《实用妇科内分泌电子杂志》
2024年第11期52-54,58,共4页
Electronic Journal of Practical Gynecological Endocrinology
关键词
米索前列醇
产后出血
出血量
凝血功能
Misoprostol
Postpartum hemorrhage
Bleeding volume
Coagulation function
