摘要
目的了解山西省东南部地区机构养老人群高钾血症的患病率及影响因素。方法采用随机整群抽样方法于2017年9―11月选取山西省东南部地区16家养老机构人群进行问卷调查,并采集外周血进行实验室检查。采用logistic回归分析模型分析高钾血症的影响因素。结果共纳入研究对象523人,平均年龄为(66.20±8.61)岁;平均血钾浓度为(4.50±0.45)mmol/L,高钾血症(血钾>5.0 mmol/L)患病率为13.95%(95%CI:11.02%~16.93%)。Logistic回归分析模型分析结果显示随着肾小球滤过率(estimated glomerular filtration rate,eGFR)的降低,高钾血症发生风险升高(χ^(2)=8.189,P=0.017),与eGFR>90 mL/(min·1.73m2)相比,60~90 mL/(min·1.73m2)与<60 mL/(min·1.73m2)高钾血症发生风险分别为4.11倍(OR=4.11,95%CI:1.06~16.01,P=0.042)和6.04倍(OR=6.04,95%CI:1.64~22.17,P=0.007)。结论山西省东南部地区机构养老人群中高钾血症患病率较高,eGFR低水平为高钾血症发生的危险因素。
Objective To examine the prevalence and factors associated with hyperkalemia among the elderly residing in care facilities in the southeastern area of Shanxi province.Methods A questionnaire survey was carried out on individuals from 16 care institutions in the southeastern province of Shanxi between September and November,2017.A random cluster sampling method was employed to select subjects.In addition,peripheral blood samples were collected for laboratory examination.The analysis of hyperkalemia was conducted using logistic regression to determine the contributing factors.Results A total of 523 individuals were included in this study[average age:(66.20±8.61)years old],and the average serum potassium concentration was(4.50±0.45)mmol/L.The prevalence of hyperkalemia(>5.0 mmol/L)was 13.95%(95%CI:11.02%-16.93%).Logistic regression analysis showed that the risk of hyperkalemia increased with a decreasing estimated glomerular filtration rate(eGFR)(χ^(2)=8.189,P=0.017).Compared with eGFR>90 mL/(min·1.73m2),the risk of hyperkalemia was 4.11 times with eGFR 60-90 mL/(min·1.73m2)(OR=4.11,95%CI:1.06-16.01,P=0.042)and 6.04 times with eGFR<60 mL/(min·1.73m2)(OR=6.04,95%CI:1.64-22.17,P=0.007).Conclusions The prevalence of hyperkalemia is higher in the institutionalized elderly population,and the lower level of eGFR is a risk factor for hyperkalemia.
作者
段培芬
原建慧
韩艳波
翟艳丽
冯向先
DUAN Peifen;YUAN Jianhui;HAN Yanbo;ZHAI Yanli;FENG Xiangxian(Department of Preventive Medicine,Changzhi Medical College,Changzhi 046000,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2024年第4期486-489,共4页
Chinese Journal of Disease Control & Prevention
基金
国家重点研发计划项目(2016YFC1300200-3)。
关键词
高钾血症
患病率
影响因素
Hyperkalemia
Morbidity rate
Influencing factors
