摘要
Background The incidence of cryptogenic stroke(CS)accounts for about 25%of ischemic stroke.Current studies have shown that cryptogenic stroke is closely related to patent foramen ovale(PFO).Evaluating the correlation between PFO and CS needs to be combined with multidisciplinary evaluation.Many clinical studies have shown that drug therapy can reduce the risk of ischemic stroke in elderly PFO patients(>60 years old).However,whether elderly PFO patients(>60 years old)can benefit from PFO closure is still controversial.This article reviewed the research progress of drug therapy and PFO closure therapy for cryptogenic stroke associated with PFO in the elderly.[S Chin J Cardiol 2024;25(1):50-56].
作者
区炜光
邓少东
陈建英
OU Wei-guang;DENG Shao-dong;CHEN Jian-ying(Department of Structural Heart Disease,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,China;Guangdong Medical University,Zhanjiang 524000,China.)
基金
supported by the National Natural Science Foundation of China(No.81370242)
the Guangdong Provincial College Students Innovation and Entrepreneurship Training Program in 2023(No.S202310571076)
the Zhanjiang Science and Technology Program(No.2022A01166/No.2022A01183)
the Non-funded Science and Technology Research Program of Zhanjiang(No.2021B01145)
the Guangdong Medical University Youth Scientific Research Training Fund(No.GDMUQ2021011)
the Universty-level Innovation and Entrepreneurship Training Program of Guangdong Medical University(No.GDMU2021163/No.GDMU2021207)。
