摘要
目的:分析鼻内镜手术联合药物治疗慢性鼻窦炎的效果。方法:选取2021年11月—2023年2月同济大学附属东方医院胶州医院收治的60例慢性鼻窦炎患者作为研究对象,随机分为对照组、试验组,各30例。对照组实施鼻窦内镜手术治疗,试验组在对照组基础上实施药物治疗。比较两组临床疗效、血清炎性因子水平、临床症状、并发症发生情况。结果:试验组治疗总有效率高于对照组,差异有统计学意义(P=0.012)。治疗前,两组白细胞介素-5(IL-5)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、白细胞介素-12(IL-12)水平比较,差异无统计学意义(P>0.05);治疗后,两组IL-5、IL-6、IL-8、IL-12水平低于治疗前,且试验组低于对照组,差异有统计学意义(P<0.05)。治疗前,两组嗅觉衰退、胀痛、头痛、鼻塞评分比较,差异无统计学意义(P>0.05);治疗后,两组嗅觉衰退、胀痛、头痛、鼻塞评分低于治疗前,且试验组低于对照组,差异有统计学意义(P<0.05)。试验组并发症总发生率低于对照组,差异有统计学意义(P=0.037)。结论:鼻内镜手术联合药物治疗慢性鼻窦炎的效果显著,可减轻炎性反应,缓解临床症状,降低并发症发生率。
Objective:To analyze the effect of nasal endoscopic surgery combined with drugs in the treatment of chronic sinusitis.Methods:From November 2021 to February 2023,60 patients with chronic sinusitis admitted to Jiaozhou Hospital of East Hospital Affiliated to Tongji University were selected as the study subjects.They were randomly divided into control group and experimental group with 30 cases in each group.The control group was given endoscopic sinus surgery and the experimental group was given drug treatment on the basis of the control group.The clinical efficacy,levels of serum inflammatory factors,clinical symptoms and occurrence of complications were compared between the two groups.Results:The total effective rate of treatment in the experimental group was higher than that in the control group,and the difference was statistically significant(P=0.012).Before treatment,there was no significant difference in the levels of interleukin-5(IL-5),interleukin-6(IL-6),interleukin-8(IL-8)and interleukin-12(IL-12)between the two groups(P>0.05).After treatment,the levels of IL-5,IL-6,IL-8 and IL-12 in the two groups were lower than those before treatment,and the levels in the experimental group were lower than those in the control group,with a statistically significant difference(P<0.05).Before treatment,there was no significant difference in the scores of olfactory loss,swelling pain,headache and nasal congestion between the two groups(P>0.05).After treatment,the scores of olfactory loss,swelling pain,headache and nasal congestion in the two groups were lower than those before treatment,and the scores in the experimental group were lower than those in the control group,with a statistically significant difference(P<0.05).The total incidence of complications in the experimental group was lower than that in the control group,and the difference was statistically significant(P=0.037).Conclusion:Nasal endoscopic surgery combined with drugs in treatment for chronic sinusitis has a significant effect,and can alleviate inflammator
作者
刘栋
姚静
杨晓红
Liu Dong;Yao Jing;Yang Xiaohong(Otolaryngology Head and Neck Surgery Department,Jiaozhou Hospital of East Hospital Affiliated to Tongji University,Qingdao 266300,Shandong Province,China)
出处
《中国社区医师》
2024年第11期9-11,共3页
Chinese Community Doctors
关键词
鼻内镜手术
药物治疗
慢性鼻窦炎
Nasal endoscopic surgery
Drug therapy
Chronic sinusitis
